41 results
Primary Objective: The aim of this study is to determine a cut-off score at the PQ-16 with the CAARMS for better detection of adolescents 12-18 years at risk. Secondary Objective(s): To study the course of UHR in adolescents 12-18 years over a one…
Empathy is related to quality of life, depression, insight and social functioning and may be an important factor in recovery of people with schizophrenia. Empathy is impaired in schizophrenia, however it is not clear which elements of empathy are…
The primary goal of this study is to assess how M4M affects acceptance of antipsychotic depot medication, during the intervention and after terminating the intervention.
The goal of the present study is to gain understanding of the brain mechanisms underlying the impairment of multisensory integration processes in schizophrenia. The study will support the development of more precise criteria for the diagnosis of…
P.11: This study seeks to contribute to our understanding of factors which contribute to violence in persons diagnosed with psychotic disorders, in order to improve clinical risk assessment and guide treatment choices.
The proposed study aims to investigate the effects of a psychomotor assertiveness training by means of a multicentre randomized controlled trial (RCT). Effects will be examined at the behavioural level by means of questionnaires and interviews, and…
Primary:-To assess whether the genetic architecture of this severe SCZ phenotype differs from the broad DSM-based SCZ phenotypeSecondary:-To detect genetic associations with the current severe SCZ phenotype (case-control comparison)-To unravel…
The main goal of our proposal is to study the interaction between cognitive and emotional capacities in schizophrenia. In numerous studies patients with schizophrenia show impairments in all major cognitive domains (6) as well as impairments in the…
The purpose of this investigation is: • To examine the effect of single and multiple doses of the new drug JNJ-39393406 (the study medication) on absorption, metabolism and excretion by the body after single administration of the drug midazolam.• To…
Primary study objective Is the reduction of 1 to several antipsychotic antipsychotic associated with more relapse? Relapse is measured with the Brief Psychiatric Rating Scale (BPRS) and is defined as: - An absolute increase of> 2 on one of…
1. To compare patient outcomes during follow-up between adherents versus non-adherents with psychoeducation in patients with schizophrenia. We selected *time to (re)hospitalisation* as the most important outcome.2. To assess the prevalence and risk…
The aim of the present study is to investigate the semantic network of patients with psychosis with current auditive hallucinations, patients with psychosis without current auditive hallucinations, first degree relatives of patients with psychosis…
The main goal of the study is to develop and validate a device that provides an objective measure of degradation of motor performance in elderly people. The device will assist to diagnose neurodegenerative disorders in the elderly at an early stage…
Hypotheses of the study:Psycho-education coping skills training is effective in reducing the negative consequences of stigma in people with SMI, in a way thata) quality of life of people with SMI improves;b) social functioning of people with SMI…
In preparation for a multicentre randomized controlled trial (RCT) we want to test the psychomotor assertiveness training in a feasibility study. The aim of this study is threefold: 1) We want to evaluate and improve intervention protocol also using…
The general purpose of the present study is to test whether people with schizophrenia perform differently when assessing working-memory tasks measuring different components. A better knowledge of working memory impaiment in schizophrenia could lead…
HypothesisChildren and adolescents with non-psychotic psychiatric disorders represent a vulnerable group high prone for psychotic symptoms. In contrast with normal populations more pronounced symptom and cognitive profiles will be found predicting…
This study examines two two forms of crisis card: (1) crisis card formulated with an independant consulant, (2) crisis card formulated with a clinician.The background of the comparison of the two forms of intervention is that the crisis card…
The aim of the present study is to investigate the neural correlates of the semantic network of patients with recent non-affective psychosis, first degree relatives of patients with psychosis and healthy controls. Furthermore, the relationship…
In the present study we are interested in the interaction between these two deficits in patients with schizophrenia using faces as visual objects. One of the important issues that will be addressed is that if the emotional content represented by the…