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The putative role of keratoconjunctivitis sicca in the development of blepharoptosis.

The main objective of this study is to demonstrate whether the number of patients with symptoms of dry eyes is significantly higher in patients with ptosis.

MULTINATIONAL, MULTICENTRE, PROSPECTIVE, LONG-TERM SAFETY AND EFFICACY FOLLOW-UP STUDY AFTER AUTOLOGOUS CULTIVATED LIMBAL STEM CELLS TRANSPLANTATION (ACLSCT) FOR RESTORATION OF CORNEAL EPITHELIUM IN PATIENTS WITH LIMBAL STEM CELL DEFICIENCY DUE TO OCULAR BURNS

Primary Objective:To demonstrate the long term safety of one or two ACLSCT(s) in patients suffering from moderate to severe LSCD secondary to ocular burns. Secondary Objectives:• To evaluate the long-term efficacy of one or two ACLSCT(s), the degree…

Multinational, multicentre, prospective, open-label, uncontrolled clinical trial to assess the efficacy and safety of Autologous Cultivated Limbal Stem Cells Transplantation (ACLSCT) for restoration of corneal epithelium in patients with limbal stem cell deficiency due to ocular burns

Objectives in adult patientsPrimary Objective:To demonstrate the efficacy of Holoclar® at one year after the first treatment in patients suffering from moderate (vascularization in two-three corneal quadrants with central corneal involvement) to…

Personalized 3D ocular prosthesis vs Conventional prosthesis

The aim of this study is to compare the 3D designed prosthesis with the conventional made prosthesis.Study questions:- How is the 3D designed prosthesis compared to the conventional prosthesis? The final chosen workflow and settings will be applied…