209 results
• To evaluate the safety of up to 3 additional courses of oral QLT091001 administered once daily for 7 days in subjects with LCA or RP caused by RPE65 or LRAT gene mutations who have been treated previously with a single 7-day course of QLT091001 in…
The main objective is to determine the Ocular Surface Disease Index (OSDI) outcomes of autologous and allogeneic SEDs compared to baseline values.
To simplify the operational technique for the eye surgeon. To minimize the risk of complications which occur occasionally with the standard technique, such as glaucoma and cataract. In addition, the surgery is less burdensome to the patient since…
To evaluate the safety and efficacy of abicipar (2 mg), compared to 0.5 mg ranibizumab in treatment-naïve patients with neovascular AMD.
The objective of this investigation is to describe visual outcomes and assess the safety at 12 months (330 - 420 days) post bilateral implantation of the AcrySof® IQ PanOptix* Presbyopia correcting IOL Model TFNT00.
Development of a method and diagnostic instrumentation for characterizing the peripheral ocular characteristics of normal subjects (with healthy eyes) in a clinical setting.Primary objective of the study: To measure the distribution of the ocular…
To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of 2 dose strengths of Bimatoprost SR in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) after initial and repeated administrations
Primary Objective:To demonstrate noninferiority of ACRYSOF IQ PanOptix presbyopia-correcting IOL Model TFNT00 to the AT LISA tri IOL Model 839MP in mean photopic binocular uncorrected intermediate (60 cm) visual acuity at Visit 4A.Secondary…
The objective of this trial is to assess the effects and costs of DMEK vs. DSAEK in order to determine whether the new technique is effective and cost-effective over the standard technique.
The primary objective is to show a difference in responder rates between the study product (T4020) and the vehicle : a reduction of 50% or more in keratitis/ulcer area from baseline (inclusion visit = V2 = Day 0) assessed at Day 28 (Visit 6).
The main objective is to determine whether the administration of allogeneic serum micro eye drops using the mu-Drop device is non-inferior to the conventional sized drops in terms of effectiveness and safety.
To monitor the effect of the free plate technique in Baerveldt implant surgery on the postoperative eye motility.
Primary: to compare the treatment effect of ranibizumab PRN (visual acuity loss and/or SD-OCT disease activity guided retreatment) versus aflibercept bimonthly regimen on central retinal thickness stability as measured by mean fluctuations between…
The objective of this study is to compare the efficacy and safety of the preservative-free fixed-dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to those of tafluprost 0.0015% and timolol 0.5% eye drops given as individual…
The primary objective of this study is to compare the quality of vision following toric IOL implantation and monofocal IOL implantation. The secondary objectives are to compare uncorrected distance vision, spectacle dependence, residual refractive…
Primary objective:To demonstrate that the mean change from baseline in Best Corrected Visual Acuity (BCVA) over a 12 month treatment period obtained with either a 0.5 mg ranibizumab *Treat and Extend* (TE) dosing regimen with adjunctive laser, and/…
To determine the aberration pattern of the cornea from its shape.
The primary purpose is the efficacy of occlusion therapy initiated in patients with untreated amblyopia between twelve and forty years of age. The secondary purposes are rate of recurrence, refractive adaptation, and the social-economic and ethic…
To investigate the additional value of partial endothelial trepanation (PET) in a deep anterior lamellar keratoplasty (DALK) procedure in terms of efficacy and safety in patients with keratoconus.
The purpose of this research study is to demonstrate that the fixed combination brinz/brim used twice daily has a similar effect (both in terms of reduction of the eye pressure and possible side effects) as brinzolamide and brimonidine used twice…