81 results
The objective of this study is to identify potential predictors of renal fluid responsiveness.
To assess the feasibility and safety of intraoperative dual-modality imaging in patients with renal cell carcinoma with Indium-111-DOTA-girentuximab-IRDye800CW. Secondary objectives are to assess how intraoperative fluorescence imaging results…
Is the BOLD MRI able to show the difference in the level of oxygenation as a mesurement of ischemia between a in a healthy kidney (<30% renal artery stenosis) and a kidney with more than 70% artery stenosis?
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
The main objective of the study is to demonstrate the utility and safetyof the IFN-γ ELISPOT marker for the stratification of kidney transplantrecipients into low and high IS regimens. The enrichment study will testnon-inferiority of low IS regimen…
To investigate the application of magnetic resonance imaging in detecting changes in tissue water content in patients undergoing hemodialysis.
Ascertain feasibility, study burden, between-subject and within-subject variability of automated RH-PAT measurements in paediatric renal transplant recipients. Comparison of adipokines and inflammatory profiles in renal transplant recipients and…
The primary objective of the study is to evaluate the feasibility of 89Zr-bevacizumab PET imaging as a biomarker before and during treatment with everolimus in patients with metastatic RCC. 89Zr-bevacizumab PET imaging will be regarded a promising…
To dermine whether the endothelial glycocalyx is damaged by ATG therapy.
The aim of the present study is to compare the following transport characteristics for a modified 3.86% glucose PET preceded by a long (>8 hours) dwell with 3.86% glucose (PET A) and one preceded by a long dwell with 7.5% icodextrin (PET B),…
The aim of the study is to observe whether microcirculatory perfusion follows the decrease in preload caused by hemodialysis in a population with an intact and a disturbed microcirculatory autoregulation.
2. OBJECTIVESPrimary Objective: To test the proof of concept whether recombinant HLA molecules (A1, A2, B7, B8) can be used for the monitoring of the indirect allorecognition pathway in renal transplant recipients.Secondary Objective(s): To…
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
To make MRI suitable for an MRI-only workflow for magnetic resonance (MR)-guided (MR-linac) stereotactic radiotherapy for localized RCC. The objective of the current study will be MRI-sequence optimisation. Sequences will be optimized for MR-based…
To study the effect of renal clearance on the biological variation and the circadian rhythm of cardiac troponin.
Based on this background information and our preliminary data in this project we aim to perform longitudinal study in cystinosis patients to correlate clinical course under cysteamine therapy and 1) Markers of macrophage activation in patients…
In the current study, we intend to study the diagnostic accuracy of promising urine biomarkers for early detection of acute kidney injury in patients undergoing major general surgery. The study is designed to validate earlier findings in a large…
Primary Objective: Mapping the consequences of a congenital monokidney on kidney function for children with MCKD.Secondary Objective(s): - Giving recommendations about follow-up for children treated with nephrectomy for MCKD.- Defining better blood…
Primary objective:- To determine the clinical efficacy of multiple doses of 177Lu-DOTA-cG250 at MTD in patients with advanced renal cancer using RECIST criteriaSecondary objectives:- To determine the toxicity of the treatment as defined by NCI…
The primary objective of the study is to evaluate the feasibility of 89Zr-bevacizumab PET imaging as a biomarker before and during treatment with sunitinib or bevacizumab plus interferon in patients with RCC.