30 results
to determine the percentage of patients with CKD, without a history of gout or attacks of arthritis, that have tophi measured by US,DECT and clinical examination. to determine the percentage of patients with CKD, that have tophi measured by US, and…
To evaluate the efficacy of computational simulation for the planning of vascular access surgery in hemodialysis patients.
Primary:- Can carboplatin exposure in children be predicted by taking the plasma concentrations of creatinine of cystatine C into account?Secundary:- Which is the effective carboplatin exposure in the current pediatric treatment protocols?- Is there…
To establish and validate MRI as functional imaging technique of the kidney and determine the appropriate combination of BOLD MRI, phase contrast MRI and diffusion weighted imaging.
Main study:Primary objective: What are the long-term effects (i.e. after 8-week drug exposure) of the GLP-1RA versus a single dose prandial insulin onrenal hemodynamics (glomerular filtration rate/ effective renal plasma flow in basal insulin-…
to determine the normal FGF23 response in case of hypophosphatemia
Primary Objectives: 1. To assess the prevalence of AAV related damage in AAV, i.e. cardiovascular damage and impaired QOL.Secondary objectives2. To assess whether there exists an association between cardiovascular disease, QOL and disease activity…
to determine the prevalence and significance of chronic nephrotoxic effects of cisplatin therapy by 1) identifying patients with chronic cisplatin nephrotoxicity and 2) reviewing their QoL. Eventually, this could improve care in these patients
To determine the general usefulness of and a proper moment when blood should be taken for the in vitro IFN-γ assays in patients undergoing chronic haemodialysis.
The primary question is whether certain tubular biomarkers are associated with albuminuria. It is thougt that to much albumin in the pre-urine is toxic to the proximal tubulus. By measuring different kind of damage markers of different locations of…
Primary objective: to compare glucose profiles collected by CGM on days with and without haemodialysis in a group of insulin treated diabetic patients who are on regular hemodialysis treatment. Secondary objectives: o assessment of frequency and…
The objective of the current study is to determine whether the presence of donor-specific B cell memory determines whether a patient will develop graft rejection or inferior graft function, especially in kidney transplant recipients who have donor-…
To compare the accuracy of the measured GFR using bolus 51Cr-EDTA, and Gd DTPA, and estimated GFR using cystatin C and creatinine with the continuous 125I-labelled iothalamate infusion method.
Methodology (part A):(1) What is the intra-individual variation in refill? (2) Is the magnitude of the ultrafiltration rate of influence on refill? (3) Is the amount of the initial intended blood volume decline of influence on refill? Implementation…
The aim of the study is to improve the quality of life of cystinosis patients. Part of it forms neuropsychological screening in order to identify specific defects in the neurocognitive development and learning abilities. The results will contribute…
The objective of this study is to assess the diagmostic accuracy of microMRI to detect ROD in children with ESRD and metabolic bone disease by oxalosis in patients suffering from oxalosis.
To distinguish patients who tolerate fluid removal by CRRT from those who become hemodynamically instable (hypotensive) during this procedure.
Primary Objective: Validation of the Fresenius BCM in pediatric dialysis patients for the assessment of TBW and ECW using dilution techniques as the reference methods.Secondary Objective: Validation of saliva sampling for bromide concentration…
- To evaluate the effect of magnesium and phosphate supplementation on intracellular levels of magnesium and phosphate determined with different techniques.- To determine if symptoms are related to intracellular levels of magnesium or phosphate.
To investigate whether it is possible to indicate (focal) IF/TA lesions in renal allografts with MRI and compare these findings to the extent of IF/TA in the kidney biopsy that has been taken previously according to current clinical guidelines.