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Measurement of Leakage of FFP2 Respirators and Surgical Masks in Human Volunteers

Primary Objective: Assess the leakage of FFP2 respirators and surgical masks in human subjects using inhalable aerosols consisting of a solution of fluorescein in water. Secondary Objective(s): (a) Study the variability in total…

Establishing a Controlled Human Infection Model with the Chikungunya live attenuated vaccine VLA1553 in healthy volunteers

The main objective of this study is to establish a controlled human infection model for Chikungunya using the VLA1553 vaccine.Primary objectives:- To assess the infection rate induced by a single administration of the VLA1553 vaccine- To assess the…

RUTI-FREEDOM: Recurrent Urinary Tract Infections in Females Receiving Effective Education, Digital Outreach & Management - a multicenter prospective randomized controlled trial in the Netherlands

A pilot study on digital coaching in rUTI at the Urology Department of Isala tested an app-based treatment additional to standard care.[8] The app provides information on rUTI aetiology, lifestyle recommendations, treatments, and the value of…