69 results
1. Immunology and Pathology:To determine the immune response of patients with simple and complex appendicitis in order to identify markers which distinguish between simple and complex appendicitis.2.Clinical and Imaging:To analyze the differences in…
This trial will provide definitive answers with regard to the anti-inflammatory effects of Vitamin D in Crohn*s disease.
The primary objective of the research is to measure the effect of a 3 week prehabilitation program on the postoperative complications in patients with an anaerobic threshold of <11 ml/kg/min who*ll undergo elective coloretal surgery for…
Comparison of preoperative diets before bariatric surgery with a randomized non-inferiority trial in order to compare the standard VLCD with a standard diet.
In this study the effect of the pneumoperitoneum on the intestine of children is objectified by measuring the iFABP levels in the urine, as an indicator for the ischemia or damage to the intestine. To exclude any iFABP increase due to intestinal…
To identify predictive variables correlated with percentage excess weight loss, reversal of metabolic complications of obesity and quality of life and postoperative complications; to identify metabolic variables correlated with markers of the…
In the Netherlands, gum chewing has not been incorporated in the standard postoperative care after intra-abdominal surgery. Therefore a multi-center RCT was set up to evaluate the influence of gum chewing on the development of ileus. Our null…
The effect of the dipeptide alanyl-glutamine, intravenously or enterally and perioperatively given, on postoperative insulin resistance in colon cancer patients.
Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…
1) To investigate what changes are present in skeletal muscle tissue of elderly gastric and colonic cancer patients (>80) compared with younger gastric and colonic cancer patients (<60) and compared to elderly controls and younger…
In this pilot study experience will be obtained in diagnosing POCD and its risk factors, in elderly surgical cancer patients.
The main objective of the present project is to assess the impact of gender, physical inactivity, obesity, and bariatric bypass surgery on basal and postprandial muscle protein synthesis rates. This will be investigated by means of three different…
To define the exact effect of LSG with and without concomitant HH repair on the prevalence of GERD and GERD-related symptoms in obese patients who are intraoperatively diagnosed with a small HH. Furthermore, to examine the effect of LSG on the…
Our primary aim is to tackle the factors of frailty in an early phase, which is possible in elective planned surgery. We hypothesise that optimal preparation, starting 5 weeks before surgery, will reduce the incidence of delirium from 15 % to 7.5…
To investigate the feasibility and safety of a diet containing 30% caloric and 70% protein restriction given during five days in healthy kidney donors planned to undergo a live kidney donation as well as persons awaiting bariatric surgery.…
The aim of this monocenter observational pilot study is to determine the incidence and severity of gastric emptying disorders in patients with a hiatal hernia and to observe the effects of hiatal hernia repair and fundoplication on the gastric…
This study will be performed to evaluate the effectiveness of the EndoBarrier device for the treatment of obesity 3 years after surgery.
In this trial we will compare two ways of suturing the ileostomy, intracutaneous sutures or transcutaneous sutures (hence the acronym ISI-trial; Intracutaneously Stitched Ileostomy trial). There is no consensus about which technique should be used.…
Patients in whom a permanent (end) colostomy is created in (semi) elective setting are randomised between the placement of a polypropylene mesh during stoma creation and the classic method without a mesh. Primary aim: Does the use of a lightweight…
Developing an evidence-based guideline for the diagnosis and surgical treatment of children with severe gastro-esophageal reflux disease.