375 results
The main point of this study is to detect in a controlled fashion if there is a relationship between CCSVI and MS. We focus on 5 parameters indicative of CCSVI: 1-reflux in the internal jugular vein (IJV) or in the vertebral vein (VV), or both with…
Primary objectives:1. To determine image quality and diagnostic accuracy of CE-MRV using a new, optimized high resolution 3D T1 weighted volume interpolated gradient echo sequence with fat suppression (THRIVE) with both a blood pool and a…
The primary objective will be to assess whether cerebrovascular reactivity is impaired in patients with steno-occlusive disease of the vertebrobasilar artery .
PrimaryTo investigate sensitivity and specificity of 3.0 Tesla MRI and MRS for dimension and composition assessment of carotid artery plaques, in particularly those plaques with lipid rich necrotic cores (LRNC), with the aim to develop these…
The main objective of this pilot study is to evaluate the burden of an additional CTA and MRA procedure in patients, and to evaluate the quality of the CTA and MRA protocols.
To compare the confidence of the interventional radiologist in diagnosing and treating arterial stenoses and occlusions by digital subtraction angiography with contrast concentrations of 300, 240 and 140 mg iodine per ml. Also, we will compare the…
Objective 1: To prospectively evaluate the utility of C-FLOW monitor to examine status of regional CBF and reperfusion in patients presenting with acute anterior circulation ischemic stroke syndrome. Objective 2: To assess the feasibility,…
In the current study, we want to demonstrate Rienso uptake in the vessel wall in patients with cardiovascular disease and relate the uptake of Rienso to endothelial permeability.
The primary goals of this study are to: i. Identify genetic variations responsible for PLP across the whole genomeMore than 90% of SNPs are found in introns or intergenic regions and most of them are probably of little functional consequence.…
Test the optimized MRI sequences/technology against CTA as gold standard, in terms ofimage quality, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), speed, and accuracy/reproducibility of extracted quantitative parameters.
* To determine the minimum effective dose of 5-aminolevulinic acid (Gliolan) for adequate MitoPO2 measurements during upper endoscopy.
The primary objective for this study is to evaluate the cerebrovascular reactivity of HCHWA-D patients:1. To compare the (autoregulatory) function of small brain vessels in HCHWA-D patients with matched controls using the cerebrovascular reactivity…
The main objective is to show whether imaging characteristics assessed at baseline can predict clinical events in patients with a 30-69 % symptomatic carotid stenosis.
The main goal of this study is to assess the difference in local pulse wave velocity measured at three different points in the left and right carotid artery in healthy subjects and in patients with symptomatic and asymptomatic carotid plaques. As…
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
Determining the role of duplex ultrasound in patients with a clinical suspicion for temporal arteritis.Determing the sensitivity, specificity, negative predictive value and positive predictive value of duplex ultrasound in patients with a clinical…
The goal is to investigate wether a PNH clone could be the cause of an unexplained thrombosis. In the population of patients with unexplained thrombosis a PNH clone may be the cause.The goal is to investigate whether the prevalence of PNH clones is…
We aim to i) describe flow patterns and flow-related dynamics in the ascending aorta of patients with aortic valve stenosis, ii) compare these flow parameters before and after surgical aortic valve replacement and iii) compare flow parameters with…
Primary Objective: To assess the analytical performance of the cardiac reader Secondary Objective(s): To assess the user friendliness of the device (handling, analytical speed).
See chapter 'objectives' of study protocol (page 12)