16 results
Rationale: Approximately, 10-20% of older adult patients present with non-specific complaints (NSCs) at the emergency department (ED). NSCs are known as poorly described symptoms, such as ‘weakness’ and ‘fatigue’, often leading to an extensive…
This study has been transitioned to CTIS with ID 2024-514049-13-01 check the CTIS register for the current data. to study the anti-tumor effect of cannabis oil (THC10% / CBD5%) in untreatable advanced HCC patients based on imaging using RECIST and…
This study has been transitioned to CTIS with ID 2024-513186-39-00 check the CTIS register for the current data. Primary objective:To evaluate the efficacy of nivolumab in combination with ipilimumab in molecular pre-selected patients with…
This study has been transitioned to CTIS with ID 2023-509675-16-01 check the CTIS register for the current data. Our objective is to study if reduced anticoagulation targets diminish bleeding complications without an increase in thromboembolic…
To assess achieved immunity against COVID-19 across the different age groups in The Netherlands by testing a representative part of the Dutch population for the presence of SARS-Cov-2 specific antibodies in serum
Primary Objective: Assess if the structure, composition and/or barrier function of the biliary HCO3- umbrella is intrinsically altered in cholangioids and liver biopsies derived from fibrosing cholangiopathy subjects compared to non-fibrosing…
The aim of the study is to compare transthoracic esophagectomy versus transhiatal extended gastrectomy in patients with GEJ type II tumors. It is hypothesized that esophagectomy allows for a higher rate of radical resections and a more complete…
This study has been transitioned to CTIS with ID 2024-511340-29-00 check the CTIS register for the current data. Primary Objective: Evaluate if testosterone replacement therapy (TRT) in (a)symptomatic testosterone deficient men with prostate cancer…
To study the effect of voxelotor on the hemodynamics of the cerebral vasculature (CBF and CVR)
The primary aim of this study is to assess whether repetitive morning, daytime or pre-night spot urine sampling can accurately estimate dietary Na+ intake and to determine the number of spot urine collections that are needed. We will assess whether…
This study has been transitioned to CTIS with ID 2022-502482-17-00 check the CTIS register for the current data. This study will evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab in patients…
The primary objective will focus on both the difference in incidence and disease severity of COVID-19 between patients with a chronic inflammatory disease and the control group.
To develop a pharmacokinetic (PK) model for the relationship between dosage, blood concentration and infection site concentration, estimating covariates to determine differences in antibiotic concentrations in synovial fluid, synovial tissue and…
This study has been transitioned to CTIS with ID 2024-518652-23-00 check the CTIS register for the current data. Investigating the long-term safety of personalized cholic acid treatment in patients with defects in bile acid synthesis based on…
To proof feasibility and safety of direct SEMS placement for palliative treatment of perihilar cholangiocarcinoma.
This study has been transitioned to CTIS with ID 2024-515703-19-00 check the CTIS register for the current data. The objectives of this follow-up study of the EPITOPE study are:• To assess the clinical benefit of Viaskin Peanut after up to 3 years…