359 results
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
Primary Objective: To determine the safety and tolerability of NF135.C10 sporozoite immunization under chemoprophylaxisSecondary Objectives:• To determine the dose-dependent protective efficacy of NF135.C10 CPS-immunization against homologous…
Pre-operative comprehensive digital Cardiac Counseling (prehabilitation) will reduce the cumalative incidence of MACE at 1 year postoperatively in patients operated for a cardiovascular procedure.
The objective of this study is to assess the performance of the Masimo O3 regional oximeter on somatic tissue oxygenation, under controlled hypoxia. Somatic rSO2 values will be compared with combined arterial and venous blood gas measurements from…
This study aims to further reduce the incidence of a post-ERCP pancreatitis by administrating a single gift antibiotics after the procedure.
The primary objective of this project is to investigate whether using prognostic factors from the PD, NP and PP domain will lead to a better prediction of treatment outcome in veterans with PTSD. Our secondary objective is to investigate whether the…
1. To evaluate if breastmilk of mothers who recovered from a proven COVID-19 infection contains antibodies (IgA) against SARS-CoV2.2. To evaluate if these antibodies are still present after pasteurization according the Holder method.
The objective of this study is to demonstrate the superiority of Distal Transradial Access (DTRA) to Conventional Transradial Access (CTRA) regarding forearm radial artery occlusion (RAO) using the 6Fr Glidesheath Slender (GSS).
Primary:- To evaluate the safety and tolerability of NT-0167 in healthy volunteersSecondary:- To evaluate the pharmacokinetic (PK) profile of NT-0167 in healthy volunteers after the administration of single ascending (SAD) and multiple ascending…
To determine differences in omics data sets of several biological layers between men and women withand without NAFLD and investigate to what extent these signatures contribute to NAFLD development.Therefore, we will establish a reference repository…
- To compare the pharmacokinetics (PK) of glepaglutide after a single subcutaneous (SC) administration by vial/syringe and by autoinjector.- To evaluate the safety and tolerability of glepaglutide following SC dosing in healthy subjects.
The objective of Study M14-675 (Phase 3 induction) is to evaluate the efficacy and safety of upadacitinib 45 mg once daily (QD) compared to placebo in inducing clinical remission (per Adapted Mayo score) in subjects with moderately to severely…
Primary Objective• To evaluate the local safety and tolerability of INM-755 cream following repeated once-daily topical applications for 14 consecutive days on wounded skin of healthy volunteers. Secondary Objectives• To evaluate the systemic safety…
The primary objective of this study is to study whether driving ability may be affected in de novo, treatment naïve PD patients, by comparing their driving simulator performance to age- and sex-matched healthy controls (HC). The secondary objective…
The primary objective of this study is to investigate the effects of classical conditioning with intranasal insulin on endogenous insulin and glucose levels in diabetes type-2 patients and healthy controls. Additionally, we will examine the effects…
To determine the long and short term outcomes of posterior colporrhaphy with and without levator sutures. To compare both groups and maybe give a scientifically proven answer to the question which one has a better outcome. Then we can offer our…
Primary ObjectiveTo evaluate whether lenvatinib in combination with ifosfamide and etoposide (Arm A) is superior to ifosfamide and etoposide (Arm B) in improving progression-free survival (PFS) by independent imaging review [IIR] using Response…
The primary aim of this study is to investigate the safety and feasibility of ultra-high field magnetic resonance imaging (MRI) of the brain in neonates and to optimize scan protocols.
To compare stent expansion after plaque modification by IVL or balloon predilation in severely calcified coronary lesions assessed by optical coherence tomography (OCT).
The goal of the study is to develop a state-of-the art- lifestyle intervention that is achievable and acceptable for patients with a bipolar and severe recurrent depressive disorder. and patients in general practice with depression