18 results
To test the cost-effectiveness of the psycho-educational intervention HypoBewust (HB) compared to care as usual.Research questions:1) Does HB significantly improve a) health related outcomes and b) societal costs after 6 months?2) Are the expected…
The aim of the study is to compare the radiological outcome of three different biocomposite interference screws (BIS) in two different ACL-reconstruction techniques with reference to TW, absorption and clinical follow up after three years.
Evaluate the safety and effectiveness of four cementless Taperloc versions: Taperloc Complete Reduced Distal and Taperloc Legacy Full Profile Reduced Distal compared to Taperloc Complete Full Profile and Taperloc Legacy Full Profile in primary THA.
To investigate lesion detection in patients with liver metastases of colorectal cancer with [18F] FLT-PET compared to CT at baseline (= gold standard). This investigation will be done based on a qualitative assessment of the scans ([18F] FLT-PET and…
To assess the effect of an infant formula with an optimized amino acid composition and a lower total protein content during the first four months of life on infant growth. Amendment follow-up study: To assess the long term effect of the intake of an…
To investigate the long term stability (> 5 yrs) in patients treated with mandibular distraction osteogenesis (MDO) for correction of a Class II-occlusion. Hypotheses:1) MDO is a technique for mandibular lengthening with comparable stability…
To evaluate whether no utilization of compressive stockings is as effective as wearing a Class II Thrombo Embolic Deterrent (TED) stocking for 4 hours. Primary outcome is leg volume on post-operative day 14.The secondary objective is to study the…
Aim of the study is to develop an intraoperative technique for SLN mapping in colon cancer which is suitably in daily practice in colon surgery in an average hospital setting.
Primary Objective: • Is there a minimal clinical difference (NRS >2) in pain levels between subjects receiving an arthroscopic debridement with a subacromial bio-absorbable Balloon and solely arthroscopic debridement in subjects with…
The aim of this study is to reduce the indication for RT without compromising cure rates. To investigate if intensified consolidation therapy (DECOPDAC-21) compared to standard consolidation therapy (COPDAC-28) can compensate for reduction in RT.
The overall aim of this study is to investigate the pathophysiology of PPMD, and identify predictors of longitudinal outcome.Primary Objective: The primary objective is to investigate the underlying neurobiology of first-onset PPMD using…
In this randomized controlled phase III study we will evaluate whether TIL infusion preceded by non-myeloablative chemotherapy and followed by high dose bolus interleukin-2 can result in an improved progression free survival when randomly compared…
The primary objective of Phase 1 is to evaluate the safety of KTE-X19.The primary objective of Phase 2:ALL Cohort:Is to evaluate the efficacy of KTE-X19, as measured by the overall complete remission rate defined as complete remission (CR) and…
To generate high quality empirical evidence for the effectiveness in terms of proportion of patients experiencing complications, quality of life and costs of initial non-operative treatment strategy (reserving appendectomies for those not responding…
The main objective of this study is to demonstrate treatment efficacy of MR-HIFU ablation of breast cancer. Effective treatment is defined as 100% necrosis of the targeted primary breast tumor. The secondary objective is safety of the MR-HIFU…
>Primary objective:During the intervention period (from randomisation until and including Term Equivalent Age [TEA]): To investigate the effect of the test product vs. the control product given to preterm infants born at 24+0 to <30+0…
The study is designed to investigate why withdrawal of off-label antipsychotic drugs for behavioral problems in people with intellectual disability often fails by comparing two blinded groups (withdrawa group versus control group). This has led to…
The aim of the PELICAN trial is to investigate the survival benefit of RFA followed by chemotherapy as compared to standard palliative chemotherapy alone in patients with LAPC.