14 results
Objective 1: Compare the predictions of the EzaPredictive 1.0 ML models for hospital admission, ER LOS, and hospital LOS with healthcare professional predictions. Objective 2: Assess healthcare professional experience and acceptance of EzaPredictive…
To evaluate local complement activation/depositions after intradermal LPS challenge
The primary objective of this study is to determine changes in monocyte-derived TNFa production after total knee replacement surgery in elderly. As secondary objective, additional parameters of immune functioning will be assessed. In addition, the…
This is a feasibility designed to investigate the feasibility of collecting QoL information from patients via digital tools. By feasibility, we mean the assessment of the uptake of the tool, the compliance to schedule and the quality of the data…
Electromyography to assess change in muscle activity as a result of intrathecal baclofen treatment
Our primary objective is to translate an in non-human primate established online TUS protocol to humans. To this end, we will investigate how this protocol influences choice behaviour in humans, by stimulating the left and right FEF in a saccade…
The primary objective is to gain information regarding the natural course of SFN and the change over time of the diagnostics using clinimetrically sound outcome measures representing various levels of outcome assessment. The secondary objective is…
The purpose of this study is to examine the effect of exogenous ketone body supplementation on carbohydrate metabolism during exercise.
To explore the effect of additional protein in plant-based drinks. In addition, gastric protein coagulation will be examined for one of the plant-based drinks and compared to that of bovine milk.
To sequence the GBA1 gene in Parkinson*s disease patients to identify possible participants for a possible future phase 1 trial. The gene will be described as wildtype (WT) or containing a mutation (GBA+); with record of the specific mutation. To…
The primary objective is to determine whether there is a difference in the capability of the patients to successfully follow the instructions of both the Levodopa Cyclops* and the INBRIJA® inhaler during an off episode, based on the instruction…
The main goal of this study is to determine motor, cognitive, behavioral, executive, and language functioning of children with PAIS at school age. Furthermore, we will analyze the effect of PAIS on brain growth, development, and connectivity using…
The goal of this study is to evaluate the effectiveness of an individualized treatment trajectory in which the order of trauma therapy for the parent, trauma therapy for the child and attachment-based therapy is tailored towards the complex needs of…
Part 1: Assess the natural disease course of three congenital myopathies during 24 months. This will enable us to obtain a detailed assessment of the phenotype and genotype, evaluate and optimize the current care, determine the rate of disease…