34 results
The first objective of this study is to gain insight in which neurocognitive and neurobiological processes underlie the development of externalizing behavior (in specific aggressive behavior) in the first two years of life. The second objective is…
There are two objectives for this study: first, to find specific serum beta cell damage markers that can serve as a clinical predictive tool for beta cell allograft loss. Second, to compare quality of life and diabetes-related outcomes in patients…
Our primary objective is to identify which intrinsic defect in Tregs is crucial for sarcoidosis pathology. To this end we will examine the genetic and functional properties of Tregs in the peripheral blood and at the site of disease, i.e. the lung…
The objective of this trial is to characterize annually the safety and durability data through 10 years in a subset of subjects randomized in the SURTAVI trial.
To study the long-term effects of interferon-α treatment for chronic hepatitis B patients infection.
Original study:The goal of this study is to have a theoretically based understanding of how sub processes of self-concept development emerge in relation to each other. The primary objective is to test a neuroscientific model of self-concept…
Primary objective: to investigate the intra- and interfraction motility of the CTV (the primary tumor as well as any affected celiac lymph nodes) in radiotherapy for esophageal cancer, and to determine adequate CTV-ITV margins.Secondary objective:…
This study aims to determine the normal distribution of desmosine in a healthy population and a population of patients with COPD (ranging from GOLD I-IV). In addition, the inter-day variation and the correlation with 24-hour urinary desmosine will…
In this study we want to prospectively investigate in a large ambulatory surgical cohort in which patients glucose levels increase during surgery and whether this is related to postoperative complications.
The objective for this trial is to evaluate an invasive strategy using urgent PCI (<3h) as compared to an early PCI (24h) using novel quick acting antiplatelet therapy.
Primary Objective: The treatment result expressed as the proportion of successful treatments per treatment arm (successful = VUR <= grade 1 and/or no urinary-tract infections 6 months after the operation) does at least not show a significant…
The primary aim of this study is to evaluate the feasibility, clinical effectiveness and cost effectiveness of a caregiver mediated exercises programme combined with e-health services (CARE4STROKE+) to improve self-reported health status and reduce…
We hypothesize that the new MRI protocol will be sensitive enough to detect a diagnostic change of >= 50% change from the normal shaped trachea. The primary objective of this study is to determine sensitivity, and specificity, of our MRI…
Determine the potential impact of a set of cognitive games in people with cognitive difficulties after stroke.
To establish the incidence and consequences (impairments op body functions, limitations in participation) of traumatic brain injury in children and youth in a region of The Netherlands as well as the incidence of the same symptoms in a group of…
To determine prevalence of HPV infection before and after renal transplantation. Secondary objectives are to determine the incidence of HPV infections before and after renal transplantation and the genotype of the HPV infections per time point, and…
The main objective is to determine if assisted hatching improves the live birth rate in poor prognosis patients. The secondary objective is to gather information on the safety of assisted hatching as determined by the number of congenital…
Our overall objective is to better understand the role of regulatory B cells in disease pathogenesis and to better predict disease flares in order to individualize treatment.
The Primary objective is to quantify the Short Range Stiffness dynamics after stroke in order to quantify the tonic muscle co-activation.
In this research, psychofysical tests will be used to explore in which way the signal processing in CI and hearing aid can be optimized to fully exploit both input modalities in speech understanding, and in sound localization..