50 results
Main objective: To evaluate the outcomes of the PelFIs in patients with OAB; the relation to the clinical efficacy of antimuscarinic treatment and to hyperactivity of the pelvic floor muscles.Secondary objectives:• To asses the efficacy of…
In a previous prospective study(4), we investigated in detail the effect of OCs on LTG clearance. However, LTG is frequently used in combination therapy. This raises the question as to what extent and how co-medication with other anti-epileptic…
To document cardiac function before and after treatment of CS.
The main objective is to measure the effect of unilateral forced nostril breathing on neural activation, specifically the hemispheric activation controlateral to the breathing nostril.
In the current study we will measure CVI in ASA 1-3 patients during elective abdominal surgery under fentanyl/sevoflurane/epidural anesthesia. We will monitor patient movement as primary correlate to CVA and cardiovascular parameters as secondary…
In this part of the project we use two 'categories' of test outcomes: false positives and positive test results for a metabolic disease that was not tested. Objectives of the study are to evaluate these categories of test outcomes by…
Primary aim of the study is to evaluate the efficacy and safety of intramuscular magnesiumsulphate in CRPS I patients during 3 weeks dose escalation study.
The main objective of this study will be to assess whether an additive stimulation of the posterior tibial nerve (PTNS) in combination with bladder training has a significant reduction in frequency of micturition in patients with overactive bladder…
What is the diagnostic accuracy of the schoolAMPS for children with DCD in the age of 6 to 11 year, compared to typical developing children in the same age, in the Netherlands? With diagnostic accuracy is meant: is it possible with the schoolAMPS to…
The primary objective of the current study is to investigate whether administered beta-blocker (propranolol) affects the following components of the EEG: the emotion-induced LPP, the vigilance-related P3, and the error-related Pe. To this end we…
The objective of the study is to protract the sleep related complaints of patients with a carotid body tumor, especially with patients with a carotid body tumor. Patients will be divided in groups based on having a single sided or double sided GCT.…
This amendment (extension to CRT-D subjects) aims to assess the economic effects of HM technology vs. classical follow-up of CRT-D patients from two perspectives: 1) the cost-effectiveness for the payer of health care, and 2) the economic impact on…
a. analysis of the usefulness of new molecular biological techniques in the diagnostic process of short stature, especially the detection of small chromosomal anomalies.b. identification of genetic factors causing short stature or influencing the…
• To determine the sleep pattern in patients with DM1 with validated questionnaires with a special focus on sleep duration, - quality and daytime sleepiness. • To investigate the association between sleep parameters and glucoregulation (HbA1c), we…
The main objective is to assess the causational factors (genetic factors within r(X) or the marker chromosomes, genetic factors within the other X chromosome and genetic factors within the autosomes) in the development of mental retardation,…
- Demonstrating an association between oxypurinol concentration and the chance of succesfull lowering of urate concentration in gouty patients (defined as reaching urate concentrations < 0,30 mmol/l)
The aim of the proposed study is to investigate the link between uncertainty reduction and the reward system, as well as the link between uncertainty induction and conflict, by means of an event-related fMRI study. We expect that uncertainty will…
Primary objective:To assess the overall feasibility of undertaking a definitive randomized controlled trial on the effects of tailored inhaler education by the GP/nurse supported by a smart spacer, in primary care treated adults with asthma.…
Objective: The Directed Anger Protocol (DAP) is an EMDR-based treatment for anger symptoms and revenge urges. Although professionals working with the DAP express positive results in lowering anger symptoms and revenge urges, no quantitative research…
In this project we intends to study the therapeutic potential of a personalized fibre mixture in individuals at high risk of developing T2DM, and aims to address the following key objectives: 1. To investigate whether a mixture of fermentable…