12 results
Objective: The Directed Anger Protocol (DAP) is an EMDR-based treatment for anger symptoms and revenge urges. Although professionals working with the DAP express positive results in lowering anger symptoms and revenge urges, no quantitative research…
Collagen barrier membranes are widely used for ridge preservation applications. Once an extraction socket is filled with a bone filler and covered by a collagen membrane, guided bone regeneration (GBR) is observed due to the barrier function of the…
Main objective is to determine short and long term efficacy of GAG therapy (bladder instillations) for people with BPS-IC H+ as compared to placebo treatment on dominant symptoms such as pain. Secondary objectives are to determine the 1) cost-…
The rationale for conducting the PARADIGM study is to evaluate the safety and effectiveness of the AVP III for closure of PVLs. Until recently, current treatment in the US and OUS included off-label use of various occluder devices. The study will…
The primary research question of the trial is to assess whether foot drop, caused by peroneal nerve entrapment in adult patients* recovers better within 9 months after decompressive surgery compared to prolonged standard conservative treatment. *…
Inguinal removal of sentinel nodes (SN) is a routine procedure for vulvar cancer, but despite using blue dye and injecting a radioactive tracer, finding the SN can be very challenging in some patients. In this study, we will investigate the…
Assessment of the Axone micro quadripolar electrode for enhanced cardiac resynchronization therapy.A clinical study designed to obain the CE-mark.This new, quadripolar micro electrode allows for easier placement of the left ventricular lead,…
The primary objective is to assess the in vivo wear of the two randomized polyethylene insert types N2Vac and X3 10 years after surgery. The secondary objective is to assess the migration and long-term survival of the Triathlon CS Peri-Apatite…
The primary objective of the trial is to assess a non-flat dose-response curve and to evaluate the dose-response relationship for 3 oral dose regimens of BI 1291583 versus placebo, on the primary endpoint, time to first pulmonary exacerbation up to…
The primary goal is to assess the survival rate of dental implants placed in cleft patients compared to non-cleft patients. Secondary objectives will be: evaluation of the parameters on the survival of dental implants (smoking, oral hygiene, length…
To determine the factors that contribute to response to CAR T-cell therapy, both at the tumour-end, as well as on the T-cell side to understand mechanisms of efficacy and immune escape in order to optimize this treatment and to reduce toxicity
The primary objective is to explore whether participation in ST leads to a change with regard to cognitive distortions and treatment motivation in behaviorally at-risk adolescents. Secondarily, it will be analysed whether participants show a…