18 results
We hypothesize that sleep apnea screening, using a combination of an online questionnaire and high resolution overnight oximetry, can safely be applied to exclude sleep apnea with high sensitivity (≥97%) and acceptable specificity (≥60%) in patients…
Our objective is to evaluatie the effect of an online, psychologist-guided intervention (eMBCT) on fatigue, stress and overall QoL in patients with sarcoidosis. Not only patient-reported outcomes, but also objective markers such as hair cortisol…
To test the clinical efficacy of vibrating socks, a new tactile cueing device, for the management of FOG in patients with PD.
Primary Objective: * To evaluate the presence and time of occurrence of a niche in women who underwent a caesarean delivery Secondary Objective(s): * To evaluate changes of niche size and thickness of the residual myometrium over time* To determine…
Primary objective:• To assess the safety and feasibility of adding ipilimumab-nivolumab to a CRT induction protocol• To assess the efficacy of adding ipilimumab-nivolumab to CRT on the likelihood of a pCR and MPRSecondary objectives: • Local and…
Primary objective: Response to trametinib treatment defined as a tumor volume decreases from baseline of >=20%, monitored by using volumetric MRI analysis. Secondary objectives are: patient reported outcomes of pain and disability and quality…
The aim of this multicenter open-label, randomized controlled trial is to investigate the superiority of 5 days (extended) versus a single dose of cefazolin prophylaxis in revision arthroplasty of the hip and knee.
To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient clinic, as well as…
Determing the relation between postoperative deltoid volume and clinical outcome following reversed shoulder arthroplasty after 2-13 years of followup.
The primary objective is to assess the adaptive T cell response to VIT in HVA patients with underlying ISM (ISM+) after treatment induction (at thirteen weeks) and upon reaching maintenance dose, after seven months, in comparison to the baseline…
The main objective of this study is to look at the effect of iv acetate infusion on postprandial glucose metabolism and whether this effect differs between healthy lean subjects and obese subjects with metabolic syndrome.The secondary objectives of…
Primary Objective: 1. To determine the non-inferiority of pre-hospital risk stratification and care path selection through the preHEART algorithm as compared to usual care with respect to the occurrence of unexpected serious adverse events (USAE) in…
Non-invasive localization of the origin of idiopathic ventricular arrhythmias
1. To unravel which factors (altered CPP, structural, functional, metabolic, inflammatory and psychological factors measured presurgical) are predictive for an unsatisfactory outcome 1 year after a primary TKR (longitudinal).2. To unravel the…
* To examine the effects and interactions of individual and environmental factors on the onset and course of mental health problems in adolescents and young adults. * To examine the effects and interactions of individual and environmental factors on…
To investigate neural response patterns to visually and orally presented palatable (high vs low caloric) and unpalatable (high vs low caloric) foods in AN patients and matched healthy controls (HC). This will be investigated through 1 study with 2…
This study investigates the correlation between IOS and the severity of fibrosis on HRCT in patients with IPF. It also investigates which IOS parameter best relates to the degree of fibrosis on the HRCT. Furthermore, as a secondary endpoint, it is…
The objective is to evaluate the effects of longer-term consumption of diets rich in boiled potatoes versus those rich in rice or pasta on established cardiovascular risk parameters.