1418 results
To dermine whether the endothelial glycocalyx is damaged by ATG therapy.
The primary objective is to identify biomarkers measured in donor and recipient blood before lung transplantation which can predict lung graft function after lung transplantation. When the risk of PGD can be predicted, more adequate therapy can be…
Quantify how many frail elderly aged over 65 years with reduced exercise tolerance and/or exercise induced dyspnoea have previously unrecognised COPD and heart failure.Quantify the difference in prevalence of unrecognised COPD and heart failure…
To investigate whether the Actiwatch® actigraph and the Everon* sensor can be helpful in the early diagnosis of a delirium. If both are able to do so, we evaluate which of the two performs best as a delirium screening device.
The primary objective in this study is to evaluate effectiveness of optimized high cervical epidural neurostimulation against placebo-stimulation in patients with intractable cervicogenic headache in a neurostimulation trial.
Demonstrate the sensitivity of the diagnostic feature "Physiological Diagnostic" (PhD) to detect clinically relevant HF-related events and to demonstrate a reasonable number of false positive indications.
Primary objectives:(1) Prevent progression of precursor lesions of the head and neck mucosa by treating selected lesions at risk for malignant outgrowth(2) Demonstrate that the detection of chromosomal instability (CIN) is indeed a powerful tool to…
Evaluation of the vascularisation of malignant lymphoma and its change during therapy with DCE-MRI. Furthermore evaluation of metabolite concentration ratios and absolute measurements made with MRS techniques as a measurement of vascularisation and…
To setup and validate an accessible, non-invasive method to enable earlier and more precise classification of patients with an elevated or high blood pressure.
To assess the effectivity and safety of 1.0 molar gadobutrol (Gadovist®) for breast MRI
To assess the effects of a screening policy for Q fever in pregnant women from areas with large numbers of Q fever cases on the pregnancy outcome and cost-effectiveness from a societal and health care perspective.
Demonstrate that the remote management system (Carelink, study group) reduces the time from device detected event onset to clinicaldecision for arrhythmias, cardiovascular disease progression,and system issues compared to patients receiving only in-…
Can we identify a gene expression profile for late radiation toxicity?
In this research, a small group of children known to suffer from complex febrile seizures (FS) will be studied. An increase in expression of FS1 will be investigated in blood in comparison with an control group. This will be done by isolating FS1…
We hypothesize that a diagnostic algorithm based on tumor site-specific VOCs enables the discrimination of lung cancer patients and controls compared to exhaled breath sampling.We aim to test this hypothesis by conducting a cross-sectional…
To determine whether CT-PET virtual bronchoscopy guided TBNA (CT-PET-VB guided TBNA) is suitable for staging MLNs in patients with suspected LC.
The main objective of this study is to obtain normal values for high-resolution manometry. The second objective is to investigate the inter- and intra-individual variability of the measured parameters.
Aims: 1. To optimize the diagnosis of M. pneumoniae infections by discriminating between colonization and symptomatic infection using quantitative PCR. 2. To study the role of host factors (age, and bacterial and viral co-infection) on infection by…
To analyze whether the sensitization profile towards hazelnut, peanut and birch pollen and their major individual allergens can be used to predict whether the hazelnut allergy is associated without/with mild clinical symptoms or severe clinical…
1. Monitoring of cellular (T-cel) specifc immune response in bladder and bloodsamples after intravesical BCG- therapy. 2. Monitoring and comparing T-cell responses after BCG therapy in patients with clinical BCG-related complications to the T-…