92 results
The primary aim of this explorative study is to compare exercise-induced cardiac troponin elevations between athletes with different levels of coronary atherosclerosis. The secondary aim is to compare exercise responses to other cardiac biomarkers…
Our primary objective is to determine whether adherence to Dutch dietary guidelines is associated with quality of life in patients with IBD. Secondary objectives are to evaluate the adherence of IBD patients to Dutch dietary guidelines, whether use…
A stepped-wedge cluster randomized trial with a clear aim to demonstrate the clinical outcomes, the mechanistical effect and the cost efficiency of prehabilitation across a wide range of patients, diseases and procedures.
The primary objective of this study is to investigate the effect of either the consumption of 1 or 3 small meals compared to no meal during the night shift on alertness levels. Secondary objectives of this study are to investigate the effect of…
The present study aims to evaluate efficacy and feasibility of an online group intervention for parents of children with cancer that focuses on the specific issues that play a role in parents coping with a child with cancer. The intervention, led by…
This project aims to evaluate the impact of an intensive dietetic care pathway on dietary protein intake and physical functioning in older adults during hospitalisation and post-discharge. In addition, the cost-effectiveness of this intensive…
To determine the feasibility of additional flushing of the fallopian tubes with Lipiodol after tubal testing with methylene-blue during THL.
The overall goal of this study is to get an up-to-date data on the incidence, disease burden, and etiology of gastrointestinal infections in the general practitioner population. More specific goals:1. Determine the incidence of gastrointestinal…
The primary objective is to compare the effects of daily beta-alanine supplementation or a placebo supplement on exercise tolerance (walking endurance time) in patients with COPD receiving NLPE.The secondary objectives are:• to determine the effects…
The goal of this study is to assess the recovery of muscle and liver glycogen stores (by ingesting carbohydrates) within 12 hours after exhaustive exercise.
Evaluate the non-inferiority of the ESP-block compared to the TEA in VATS lobectomy or wedge resection.
Primary objective: To reduce clinically relevant respiratory tract infections (including COVID-19) ind community dwelling older persons during the pandemic of SARS-CoV-2. Secondary objective: To reduce disease severity, the duration of hospital…
• To measure the quality of the red blood cells of redon drain blood before and after cell saver processing.• To measure the effects on whole redon drain blood in terms of inflammatory activation, platelet activation and blood rheology in the…
Therefore, in this study, we would like to investigate the clinical effectiveness of a smart technology intervention (The Heart Failure Box) in heart failure patients from the department of Cardiology at Leiden University Medical Center.
To explore the effect of single versus repeated preconditioning on circulating blood factors (i.e. metabolomics analysis) as a likely mechanism in patients with cSVD. Secondly, we explore whether the effects of single versus repeated preconditioning…
Main objective: We propose a proof of concept study to apply noninvasive brain stimulation, specifically tACS, for the first time to adult CG patients with the aim to find stimulation protocols that improve their motor and language performance by…
The primary objective is to compare18F-MFBG PET-CT imaging for neuroblastoma patients with the current standard of imaging, 123I-MIBG SPECT, using the SIOPEN score for skeletal lesions and the number of detected soft tissue lesions as endpoints.
In this study we aim to investigate which pathways in septic patients exacerbate endothelial injury and dysfunction, furthermore do we want to investigate to what extent, and due to which components plasma transfusion can improve the endothelial…
The aim of this study is to investigate the effect of discrete vibrotactile feedback of mediolateral weight shift and step initiation for complete SCI patients on the use of an exoskeleton.
To determine the influence of concomitant administration of tamoxifen and probenecid on tamoxifen and endoxifen(-glucuronide) plasma concentrations