125 results
The objective is to sequentially test, validate, obtain regulatory approval for, and deploy at home, a closed-loop Control-to-Range (CTR) system comprising two algorithmic components: a Safety Supervision Module (SSM) and an automated Range…
• To evaluate the safety of up to 3 additional courses of oral QLT091001 administered once daily for 7 days in subjects with LCA or RP caused by RPE65 or LRAT gene mutations who have been treated previously with a single 7-day course of QLT091001 in…
Objective: the use of autologous platelet rich plasma (PRP) as an adjunct to the staged mucosal advancement flap to achieve a better closure rate of high peri-anal fistula*s.
Primary Efficacy ObjectiveThe primary efficacy objective is to determine the long term efficacy of vagal nerve stimulation as assessed by the DAS28 score.Secondary Efficacy ObjectivesThe secondary efficacy objectives are to determine the long term…
Primary Objective: Compare functional results of the three postoperative care regimens assessed with the Olerud-Molander ankle score 12 weeks after surgery.Secondary Objective(s): 1) Compare functional results and patient satisfaction of the three…
The primary objective of this randomized clinical trial is to evaluate if perioperative SDD can reduce anastomotic leakage rate and other infectious complications while thereby simultaneously improving long-term oncological outcome. Secondary…
To investigate the effect of variations in the length of bilipancreatic limb on weightreduction in morbidly obese patients undergoing RYGB-surgery.
Objectives: The primary aim of this study is to provide evidence for the effect of ITB treatment on the level of activities in dystonic CP patients.
1) To study the late effects of 131-I treatment and TSH suppressive therapy as well as quality of life in patients with childhood-onset DTC. 2) To determine the presence of RET/PTC 1 and 3 translocations and BRAF mutations, and to investigate their…
Primary objective* To determine safety and the maximum tolerated dose (MTD) of SAR405838 through the characterization of dose-limiting toxicities (DLTs).* To assess biological activities of SAR405838 in patients with dedifferentiated liposarcoma…
The primary objective of this study is to evaluate the web-based intervention *Leven met Pijn online* for chronic pain patients in terms of a decrease of interference in daily life due to pain. The secondary objective of this study is to evaluate *…
The primary objective of the present study is to evaluate the effectiveness of the Aggression Replacement Training (ART) on aggression regulation disorder in a forensic psychiatric outpatient setting.A secondary objective is to examine how treatment…
Objective of the study: With this pilot study we attempt to explore the possibility to treat patients suffering from intractable neuropathic pain with CVS
To evaluate the effect on sleep and ptsd of the drug Doxazosin Retard in patients with PTSD who also have sleep problems.
Primary Objective: Is there reduction in pain using an abduction brace in patients undergoing arthroscopic cuff repair? Secondary Objectives: - Are there differences in function and recovery of the cuff, determined using questionnaires and echo?- Is…
The goal of this prospective study is to compare the outcome of an integrative primary care (IPC) approach with standard primary care (SPC) management of patients with chronic musculoskeletal pain. The primary outcome measure will be the change in…
see whether this treatment schedule is effective in EGFR-mutated NSCLC patients who have developed progression after treatment with EGFR-TKI monotherapy in standard dose before
The main objective of this study is to examine whether an intervention of dietary restriction and exercise can bring the phenotypic profiles (with respect to biomarkers of metabolic health) of the normative ageing controls (*partners*) towards those…
Primary objectiveTo compare the efficacy of subpurpuric pulsed dye laser treatment with different intervals between treatment sessions.Secondary objectiveTo evaluate the safety and the long-term effects of subpurpuric pulsed dye laser treatment.
To prospectively collect and assess global safety and efficacy data on the IN.PACT Admiral* Drug Eluting Balloon (DEB) in treatment of atherosclerotic disease of the superficial femoral and/or popliteal arteries in *real world* patient population.