22 results
We hypothesize that the toxic potency of UFP from air traffic is comparable to road traffic after inhalation by healthy humans. Therefore, we aim to:* Identify acute effects of short-term inhalation of ultrafine particles right next to Amsterdam…
* To evaluate the effect of EDP1815 on the systemic immune system.* To evaluate the safety and tolerability of EDP1815 in multiple formulations.
To study the effectiveness and safety of semi-annual zoledronic acid treatment for reducing articular cartilage and pain loss in knee osteoarthritis.
The key objective of the current field study is to test the effectiveness of an integrative lighting intervention to support sleep and increase self-control among AUD patients in ambulant care, and, in turn, stabilize and/or reduce alcohol…
The effect of whey and casein protein ingestion prior to sleep on overnight muscle protein synthesis
The main aim of the current study will be to assess whether the ingestion of whey protein or casein protein stimulates overnight muscle protein synthesis following endurance-type exercise.
The main objective of this study is to investigate whether intraoperative music reduces postoperative pain in patients undergoing surgery for esophageal or stomach cancer. Secondary objectives are the effects of intraoperative music on…
To evaluate the safety and efficacy of 12 weeks albendazole treatment added to anti-TNF monotherapy in adult patients with Crohn*s disease with incomplete mucosal healing.
The objective of this project is to study the effects of low levels of dietary AGEs in overweight subjects on insulin sensitivity, *-cell function, micro- and macrovascular function, and gut microbiota. The obtained insights can be used to attenuate…
The purpose of this study is to investigate how safe the new compound FM101 is and how well it is tolerated when it is administered to healthy volunteers. FM101 has not been administered to humans before. It has been previously tested in the…
To investigate whether minimally processed milk product can decrease the diarrheagenic E. coli-induced changes in reported stool frequency and gastrointestinal complaints.
Our primary objective is to compare the clinical outcome (time to and grade of symptom resolution) after 4-week-use of a whey based extensively hydrolysed formula (eHF) versus an amino acid-based formula (AAF) in children with nIgE-CMA. As secondary…
The primary objective of this study is to investigate if the addition of bovine milk fat to an infant-formula product increases the diet-induced thermogenesis. Secondary objectives are to investigate if the addition of bovine milk fat in an infant…
The primary objective of this study is:* To investigate whether a two-weeks intervention with cerebellar anodal tDCS could improve ataxia severity in SCA3 patients compared to sham stimulation.Secondary objectives of this study are:* To investigate…
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
To assess whether whey protein supplementation during the days before and after muscle-damaging eccentric exercise improves recovery of muscle strength, compared to placebo?Secondary objective(s) are: To assess whether whey protein supplementation…
Primary objective:Assess whether there is a measurable difference in the GRF in the early phase after THA with regard to gait between the DSA and the PLA.Secondary objectiveShow whether there are differences in parameters present from the gait…
The primary aim of the study is to compare the effects of protein versus placebo supplementation on 24 hour post-race delayed onset muscle soreness after strenuous endurance exercise performance among endurance runners.The secondary aim of the study…
Primary Objective: 1. To assess the impact of Winclove CLEAR on the quality of life of female rUTI patients.Secondary Objectives: 2. To assess the impact of Winclove CLEAR on the incidence of UTI and the (associated) urinary microbiota composition…
Objective: The primary outcome objective of this trial will be length of stay in the hospital after surgery. We further will analyze intra- and postoperative opioid consumption, NRS pain scores, time in the post anesthetic care unit, time to walk (…
Study A: Safety of intranasal administration of palivizumab in healthy adultsStudy B: Effect of local administration of palivizumab on prevention of RSV infection