1014 results
The proposed study has 2 main aims: 1) Understanding the complex interplay of determinants of parenting and examining how specific parenting styles explain associations between parent characteristics (such as personality or mental and physical (ill…
To improve the response rate to treatment of severe acute GVHD (grade II-IV with gut involvement ) by adding infusion of Mesenchymal Stroma Cells to standard high dose prednisolone.
Primary objectivesFor part A of the study: -To determine the feasibility of Clofarabine when given at three possible dose levels together with standard induction cycles I and II in patients with AML/ RAEB with IPSS>=1.5 in a prospective…
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes…
To establish the diagnostisch accuracy of ultrasound for the exclusion of fracture of the elbow
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
Active surveillance is non-inferior to surgery in patients with oesophageal cancer showing complete clinical response after neoadjuvant chemoradiotherapy.
NA
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
Development of blood-based monitoring techniques for treatment response evaluation and diagnostics in lymphoid neoplasms, including HL and NHL by using extracellular vesicle and cfDNA techniques for biomarker discovery, assay development and…
1A) To implement a screening-protocol for HIV related co-morbidities and their risk factors, based on multidisciplinary expert consultation, in a large HIV outpatient clinic and among an HIV-uninfected control group.1B) To assess the prevalence and…
The objective of this study is to obtain clinical performance (outcomes) data and survivorship for commercially available Zimmer Persona knee implants implanted in primary total knee arthroplasty.
To analyze the protective effect of azelastine/fluticasone propionate against exercise-induced airway narrowing by measuring inspiratory and expiratory airflow limitation and airway resistance and reactance in asthmatic children.
We aim to use quantitative [18F]Florbetaben PET to investigate a potential lateralized distribution of cerebral amyloid-β deposition in patients with COD. To validate the assumption that the hypoperfusion is lateralized, we use relative perfusion (…
The aim of this study is to investigate the effect of two distalisation techniques of a gastric bypass in revisional surgery with standardised limb lengths in total weight loss (TWL) and the need for treatment for protein calorie malnutrition (PCM…
In this pilot study we will validate intestinal mucosa biopsies for usage in scRNA sequencing and CyTOF analysis for future research in patients with CD and UC. Key in this validation is the number of viable cells in mucosal biopsies and the number…
To evaluate whether we can determine the health status of the joint by measuring biomarker levels using a newly developed assay by the University of Twente based on the multiplex measurement of a panel of relevant biomarkers using Surface Plasmon…
The primary objective is to compare the glucose curve with the OGTT, as a screening test for GDM.The secondary objective is to see if GDM treated after screening either with the glucose curve or with the OGTT, can predict perinatal complications and…
Objective: This protocol describes a framework that will be used to create different studies. The general primary and secondary objectives of this protocol are stated below:Primary objective: Investigate the effect of surgery on the position and…
To establish the safety and effectiveness of the SAPIEN M3 System in subjects with symptomatic, at least 3+ mitral regurgitation (MR) for whom commercially available surgical or transcatheter treatment options are not preferred/appropriate due to…