175 results
We hypothesize that treatment with peppermint oil will lead to a greater symptom (especially abdominal pain) reduction in IBS patients compared to placebo. This will lead to a higher total percentage of responders (as defined by FDA/EMA…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
The present study aimed to improve the performance of the A-DIVA scale by identifying predictors other than those included in the original scale. A modified A-DIVA II scale will be created which is applicable in the total hospitalized population to…
- A standardized approach by a multidisciplinary experteam will evactuate a reduction of the use of restraints in care for people with intellectual disabilities
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
1. Active sniffing decreases appetite; 2. Food choice is mainly influenced by the food odour that was perceived first.
Early nutrition in preterm infants is essential for growth and neurodevelopment. The last decades more aggressive nutrition has been implemented in clinical practice to ensure optimal growth and thereby optimal neurodevelopmental outcome, as…
A low peak E2 during COS is considered to be safer than a high peak E2 in women with breast cancer
Screening of esophageal cancer can be improved by the optical detection of field cancerization
The use of PEG-asc could contribute a significant decrease in potassium values a potentially cause serious clinical adverse events.
We hypothesize that, asymptomatic patients with severe aortic stenosis, receiving an aortic valve replacement have a better quality of life compared to patients without aortic valve replacement.
Our hypothesis is that our gradually progressive protocol offers advantages with respect to the eccentric protocol based on the protocol of Alfredson (gold standard). We expect that, because this protocol is more individualized, less pain during the…
Since bleeding risk is high in the elderly we hypothesize that clopidogrel is superior to ticagrelor and prasugrel in terms of causing lesser bleeding events and being non inferior in net clinical benefit in patients above 75 years and CRUSADE…
The aim is to evaluate molecular assays for the detection and quantification of bacterial DNA in blood from patients with bacteraemia.
What is the effect of the systemic antibiotic therapy on the number and diversity of specific bacterial groups in fecal samples of pediatric patients with cancer?
A. COMET as an additional transdiagnostic intervention focusing specifically on low self-esteem increases the effectiveness of mentalization based treatment in patients diagnosed with borderline personality disorder. B. This increased effectiveness…
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.
Aim of this prospective randomized trial (RCT) is to compare the gold standard LCW with the CWO in patients eligible for HTO who need a correction of 10 to 16 degrees. Hypothesis is that the CWO technique will achieve more accurate overcorrection of…
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…