1762 results
1. Cross-sectional: 1.1 At baseline (the start of MBT), we expect a positive association between (level of) shame proneness and measures relevant for/related to mentalization based treatment and/or borderline personality pathology, i.e. measures of…
The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.
Primary Objective To describe how patients experience the first eight weeks after shoulder arthroplasty, regarding pain and pain medication, shoulder function and quality of life. To determine the direct effect of patients' expectations on…
To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…
To test the effectiveness of a self help booklet without therapist guidance vis-à-vis a psycho-education brochure for adult problem drinkers in the general population.
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
A 10% point difference between the intervention group and control group in IDM is expected. The sample size calculation is based on a worst-case scenario with regard to precision. For a binomial distribution, the widest distribution and thus largest…
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
The hypothesis is that patients with low anti-TNF drug levels have a higher risk of loss-of-response to anti-TNF drugs compared to patients with high anti-TNF drug levels.
1) The checklist 'Attune & Stimulate' is a valid instrument to assess the arousal level of clients with SID. 2) Caregivers who are randomized to the intervention group that is instructed to use the A&S-checklist attune…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
The induction of immunity might be slower in older persons than in younger individuals. This could influence the occurence of adverse events induced by the vaccine.
In the first 6 months Liraglutide affects weight more than CBT, but CBT provides weight maintenance after 12 months.
Breast cancer is the most common type of female cancer worldwide. Early detection has proven to have a positive influence on the prognosis and survival rate. An important aid in the detection and diagnosis of breast cancer is the use of medical…
Nonsimultaneous current steered pulse trains will lead to a single pitch percept whilst reducing the amount of current in comparison to conventional monopolar stimulation
We hypothesize that medical nutrition (PN and EN) compared with no medical nutrition (only oral nutrition) will be associated with better maintenance of nutritional status (fat- and fat free (muscle) mass and body weight), functional capacity,…
To evaluate whether a dietary advice of green vegetables, beef and whole dairy products during six months including standard supportive care can decrease the TSH-level compared to standard supportive care alone in children aged 1-18 years with…
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.