345 results
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last six weeks prior to…
To study the impact of addition of the GAAD score to imaging in patients with chronic liver disease eligible for HCC surveillance.
To investigate the feasibility of Bergström needle biopsies of the vastus lateralis muscle, and NIRS measurements of the gastrocnemius muscle in post-ICU patients.
Primary objective: To assess the impact of acute laser treatment on muscle tissue mitochondrial respiration in vivo in healthy, young adults. Secondary objective: To assess the impact of acute laser treatment on muscle cellular energy, anabolic,…
The primary objective of this clinical feasibility study is to assess the overall diagnostic yield of the Investigational Device in comparison to standard care. The secondary objective is to assess the safety issues that possibly occur while using…
Hypothesis: implementation of individualized, integrated 7 Tesla MRI and MEG brain networks can increase the effectiveness of DBS by improving motor symptoms and quality of life in patients with Parkinson's disease and essential tremor.…
The aim of the current study is to determine the transport functionality, integrity, and viability in intestinal tissue obtained from patients who are expected to have a disturbed intestianl functionality due to severe obesity.
To assess the effectiveness of EMDR in RA patients with persistent pain despite inflammation being under control.
In the current study, we aim to assess the energy requirements of professional football players during different phases in the rehabilitation from an ACL reconstruction. As such, this study will identify the energy and nutritional requirements,…
To evaluate the efficacy of SBRT as additional treatment after standard care chemotherapy regarding tumor local control, toxicity, progression-free survival, overall survival and quality of life. In addition, to explore the value of immunodynamics…
The primary objective of the CRT-DRIVE study is to test the hypothesis that at least 75% of patients undergoing a CRT implantation guided by non-invasive electrical and venous anatomy assessment (XSPLINE technology) will show a reduction of left…
The primary objective is to investigate the feasibility of NIR fluorescence imaging with intra-arterial ICG to detect differences in foot perfusion following successful endovascular lower extremity revascularization.
To support the validity of an in vitro colonic fermentation system, by demonstrating that changes in gut microbiota composition and functionality/metabolism, induced by prebiotics in the in vitro Microcolon model, are mimicking the changes that are…
IRDs are genetically diverse (280 causative genes have been identified to date) (https://sph.uth.edu/retnet/) and have vastly different clinical manifestations, including age of onset, severity of disease, rate of progression, and structural and…
Objective: We aim to 1) monitor and investigate the change in serum metal ion (Cobalt and Chrome) levels postoperatively (at 3-6, 12 and 24 months) in patients receiving a primary PEEK HD coupling mechanism, monitor and investigate the change in…
Primary Objectives:Associated pharmaceutical trial:To compare the efficacy of disitamab vedotin in combination with pembrolizumab to chemotherapy as first-line treatment in participants with advanced UC that expresses HER2Clinical…
To elucidate host/microbial intestinal (postprandial) fructose kinetics (by 13C incorporation in glucose and ethanol as well as other metabolites) in small intestinal fluid as well as plasma, urine and breath samples (whole body metabolism) and…
Objective 1. To conduct an extensive needs assessment on how to promote individually tailored (sustained) lifestyle changes in individuals with multimorbidity, including vulnerable groups and ethnic minorities.Objective 1.1: To gain in-depth…
Primary Objective: To characterise longitudinal changes in biomarkers of TDP-43 pathology and oxidized lipid metabolism in ALS patients. Secondary Objective: To characterize the relationship of longitudinal changes in these biomarkers to changes in…