81 results
To compare the post-prandial muscle protein synthetic response following ingestion of a whole-food meal (560kCal; 30g protein total) before and after a 8-week passive heat treatment intervention in healthy older men and women.
This study has been transitioned to CTIS with ID 2024-518865-85-00 check the CTIS register for the current data. Primary objectiveEvaluation of [18F]MC225 to measure the P-glycoprotein function in Alzheimer*s disease, Mild Cognitive Impairment and…
We will investigate how safe the study device DV3395-C1 is when it is taken in by healthy participants. We will also look at the passage (i.e., gastrointestinal transit time) and activation of the study device. For this, we will see if the device…
Number of patients with >=80% reduction of VT burden, i.e., any ICD-treated or highly-symptomatic VT episodes, at one year after STAR compared to the year before (including VTs during the 8 week-blanking period). Efficacy parameters will be…
The primary objective is to determine the effects of iPE on the PTSD diagnosis, on the self-rated and clinician-rated severity of PTSD symptoms. The secondary objectives are to determine the effects on psychotic symptoms, depression symptoms,…
To evaluate the functioning of and experience using the newly-developed prototype prosthesis (MyLeg System) during daily activities in people with a transfemoral osseointegration implant.
In this study we will investigate the safety of the study compound IMU-838 and how well it is tolerated when it is used by healthy subjects. Please note that when the term *study compound* is used in this document, we mean IMU-838.The study will…
In this study, we will investigate how quickly and to what extent etrumadenant is absorbed, transported, and eliminated from the body. For this study, etrumadenant is radioactively labelled with carbon 14 (14C). In this way, etrumadenant can be…
This study has been transitioned to CTIS with ID 2024-511968-81-00 check the CTIS register for the current data. Studying the effect of deferiprone on the motor function of patients with Pelizaeus-Merzbacher disease.
Immunogenicity:To determine the immune response in terms of GMT fold-rise for neutralising antibodies against SARS-CoV-2 following a single booster dose with VLA2001Safety:To assess tolerability of a VLA2001 booster vaccination
To assess whether MRI Primovist could replace 99mTc-mebrofenin HBS as a preoperative functional liver assessment in addition to CT-volumetry in predicting PHLF in patients with resectable pCCA who require a major liver resection.
Primary Objective: We aim to provide a clear phenotype of the immune system in patients with FOXP1 syndrome. Secondary Objectives:We aim to correlate the immunophenotype of patients with FOXP1 syndrome with frequency and type of infections reported…
The purpose of this study is to investigate how quickly and to which extent the new study compound BI 690517 is absorbed, transported,and eliminated from the body. BI 690517 is an investigational study compound which has not yet been approved for…
This study has been transitioned to CTIS with ID 2024-515637-14-00 check the CTIS register for the current data. To evaluate the long-term safety and tolerability of elexacaftor(ELX)/tezacaftor (TEZ)/ivacaftor (IVA)
The overall aim of this study is to assess the frequency, patient-reported severity and impact of cough, and the distribution of coughing fits during the daytime and nighttime, in a population of patients with non-IPF ILDs.Primary objective: The…
REDALERT*s goal is to combine the ISPro technology and geneXplain platform to develop an integrated solution for routine RTM analysis with:A) novel processing methods for ISPro to accurately characterize the RTM and the relative abundance and shifts…
In this study we aim to use minimally invasive real-time techniques including OCT, HHGM, eNose and/or GC-MS for the evaluation of the effect of BT and determine response predictors. To evaluate innovative diagnostic techniques that might be able to…
This study has been transitioned to CTIS with ID 2024-519351-28-00 check the CTIS register for the current data. Cross validation of the hybrid tracer ICG 99 Tc Nanoscan with respect to 99m Tc Nanoscan for the determination. In particular the…
The primary objective of this study is to evaluate the incidence of hypoglycemia in adult and pediatric patients with GSD III. The secondary objective of this study is to evaluate the sensitivity of various muscle strength and function measures to…
In this study, we will investigate how quickly and to what extent the study compound MIJ821 is absorbed, transported, and eliminated from the body. For this study, MIJ821 is radioactively labelled with carbon-14 (14C). In this way, MIJ821 can be…