94 results
The aim of this study is to determine whether the presence and the extent of periodontitis are independently related to the presence and extent of coronary calcification.To determine if periodontal treatment has an positive effect on the…
The overall objective of this study is to examine specific cardio-metabolic and cardiovascular parameters in women of subfertile couples. This study protocol is divided in 3 studies to evaluate several cardio-metabolic/cardiovascular parameters in…
To map phenomenolocal characteristics of hallucinations and delusions in psychiatric and neurologic patient populations as well as in the general population. By comparing this between all groups, different subtypes of hallucinations and delusions…
The frontotemporal syndrome in amyotrophic lateral sclerosis: screen, impact, imaging and pathology.
The main objectives are: 1. to develop a diagnostic tool for the assessment of the frontotemporal syndrome. 2. To investigate the structural and functional brain networks of ALS patients with and without a frontotemporal syndrome, in order to gain…
Primary objective: To compare the NP microbiome composition and the presence of viruses in children hospitalized for a LRTI to the NP microbiome composition and the presence of viruses in healthy age- and gender-matched controls. Secondary…
The primary objective is to investigate if there is a difference in the performance on tasks measuring visual perception and attention between visual hallucinating schizophrenic patients, schizophrenic patients who do not hallucinate and healthy…
The primary objective is to assess environmental, hygiene-related risk factors for MC. Secondary objectives are the difference between the CC and LC subpopulation regarding hygiene-related risk factors, living area as potential risk factor and the…
1. to determine whether the oxidation of BCAA (leucine) is impaired in patients with T2DM and in humans at risk to develop T2DM (first degree relatives). 2. to investigate whether an altered leucine oxidation in muscle is associated with insulin…
Because the pathophysiology of SSc is unknown, there is currently no treatment available to cure the disease itself, so only individual organ system complications are treated (7,8). Therefore, treatment is patient-specific and aimed at ameliorating…
Primary objective: To identify early cognitive, neural, behavioural and bio-markers which precede the onset of clinical symptoms of ASD, through obtaining measures of eye tracking, EEG/ERP, NIRS, cognitive performance and collecting DNA and…
The main purpose of this PhD research is to obtain more insight in the interplay between psychopathology and cultural identity among refugees from Afghanistan and Iraq and to contribute to more effective treatment plans. Information about the…
to investigate whether microbial transplantation from either allogenic (healthy) or autologous (own) donor, administered through a small intestinal tube, has beneficial effects on immune status, betacell function c-peptide secretion upon mixed meal…
1. Study the BBB permeability in cSVD patients and compare it with healthy control subjects. 2. Examine the relationship between BBB permeability and cognitive function. 3. Examine the relationship between BBB permeability and the extent of…
Primary Objective: To compare the expression of inhibitory receptors SIRL-1 and LAIR-1 on blood neutrophils of patients under age 12 admitted with sepsis to the paediatric intensive care with healthy controls and intensive care patients without…
Our primary objectives are to determine whether schema-ECT increases the remission rate of a course of ECT, reduces the relapse rate, and weakens negative schemas. Our secondary objectives are to assess the neurobiological mechanisms underlying the…
In this project, we aim to study how local and systemic antibody by distinct B- and T-cell populations control periodontal health, in particular control the conversion of gingivitis into destructive periodontitis. Which types of B cell responses are…
Primary Objective: Identification of rare variants in candidate genes and regulatory elements in pediatric IBD patients. Secondary Objective(s): To determine the functional consequences of identified genetic variants in IBD, we will correlate…
-To assess the central chemosensitivity by an carbon dioxide rebreathing test-To assess mouth occlusion pressures during the carbon dioxide rebreathing test-To study the relation between these results and the results obtained with the MRI and…
The study*s objective is to measure neurobiological differences between veterans and military men with aggression regulation problems after deployment and healthy control participants.
Primairy objective: To investigate whether the sympathetic stimulation of BAT, as assessed with a MIBG SPECT-CT scan, differs between young and elderly subjects.Secondary Objectives: 1) To investigate whether the slope of the correlation between…