68 results
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
The overall aim of the study is to improve diagnostic and therapeutic options for people with CF, especially in the context of young children and novel CFTR-targeting drugs. Primary Objective: 1. to demonstrate relations between CFTR genotype,…
To explore and optimize the usability of Doppler-OCT scanning of conditions affecting any of the retino-choroidal layers.
The primary objective for this study is to evaluate the cerebrovascular reactivity of HCHWA-D patients:1. To compare the (autoregulatory) function of small brain vessels in HCHWA-D patients with matched controls using the cerebrovascular reactivity…
- To determine whether there is a mitigated immediate immune response to islet infusion in immunosuppressed recipients- To determine if complement activation during immediate immune response is affected in immunocompromised recipients
Primary Objective: To assess whether both OCT (optical coherence tomography) and/or HSI (hyperspectral imaging) detect differences in glioma tissue as compared to healthy tissue as examined during brain-surgery.Secondary Objective(s): To assess if…
To assess functional outcome and using gait analysis to quantify kinematic and kinetic abnormalities of servicemen who suffered foot injuries due to combat actions.
The main goal of this study is to assess the difference in local pulse wave velocity measured at three different points in the left and right carotid artery in healthy subjects and in patients with symptomatic and asymptomatic carotid plaques. As…
The purpose of this study is the improvement of sound material for the Sound-Ear-Check by focusing on the acoustical analysis and the validation of the Sound-Ear-Check, among adult participants and children with normal-hearing abilities and hearing-…
The aim of this pilot study is to establish Th1/Th2/Th17 patterns in healthy controls by analysing cytokine concentrations in nasal fluid (nasal wash and cotton wool method), saliva and blood. This will be done in order to give an estimation about…
The primary objective of this study is to explore the PSA response rate to cabazitaxel in mCRPC patients who have progressed to docetaxel and to correlate the PSA response to AR-V7 expression in CTCs. Exploratory objectives include documenting the…
We aim to i) describe flow patterns and flow-related dynamics in the ascending aorta of patients with aortic valve stenosis, ii) compare these flow parameters before and after surgical aortic valve replacement and iii) compare flow parameters with…
Primary Objective: To assess the analytical performance of the cardiac reader Secondary Objective(s): To assess the user friendliness of the device (handling, analytical speed).
1. Determine body composition of MD patients;2. Determine physical function of MD patients;3. Determine the association of body composition and physical function of MD patients.
The main objective of this study is to evaluate the differences in [18F]FEOBV binding between PD patients and healthy control subjects, in order to evaluate the clinical feasibility of [18F]FEOBV as a cholinergic imaging ligand in PD. Secondary…
DEfective HUman SAlivary gland stem cells: the cause of Primary Sjögren*s syndrome?
-DEHUSAPS study-
To assess whether salivary gland stem cell (SGCS) defects are key to salivary gland pathogenesis in pSS.
To demonstrate the efficacy of AdreView* imaging for appropriately guiding the decision of ICD implantation in a population of New York Heart Association (NYHA) class II and III Heart Failure (HF) patients with 25% * left ventricular ejection…
Considering the lack of consensus, we feel these mechanisms merit additional focus and research. LD transfer changes shoulder anatomy and thus affects the complex interplay in the glenohumeral and scapulothoracic joints. So far, no study has been…
We aim to identify neurobiological correlates of treatment response in children with DD and will examine how phonological and speech abilities are related to brain measures in children with DD as well as in controls. As a secondary objective, we…
This study strives for a better diagnosis of patients with posture-related headache which can increase the therapeutic success ratio and the early prevention. This approach could increase the quality of life of the patient. The therapeutic…