16 results
The overall aim of the project is to define effects of genetic and non-genetic variants on pharmacological treatment response in children with asthma. The following questions will be answered:- What are the characteristics of children who do not…
To investigate the direct effect of caffeine on the respiratory effort of the preterm infant at birth.
To non-invasively quantify pulmonary vascular remodeling in pulmonary arterial hypertension using [18F]-FLT (determination hyperproliferation).
To study the effects of changing consultations by starting with the patients agenda on the enablement of children with asthma and their parents to bring forward their questions, worries, problems and beliefs.
The main objective of this study is the clinical, physiological and psychosocial determinants of CAT in a broad sample of patients with moderate to very severe COPD and the impact of co-morbidities on the HRQL assessed with CAT. Secondary objectives…
Besides more basic research into which RNA-binding proteins and microRNAs regulate the expression of inflammatory mediators in airway epithelial cells, we will also assess these proteins and microRNAs in airway epithelial cells from patients with…
To investigate whether exposure to nanoparticles is able to induce short-term functional changes in the brain, we previously exposed human volunteers for one hour to diesel exhaust particulates (300 ug/m3) and followed their brain activity during…
What is the prevalence of depression and anxiety in children with asthma. Is this more frequent in asthma than in other chronic conditions like diabetes and Coelikie? And how compares this to healthy children in the same phase of life?
To compare the occurrence of significant mask leak when using a nasal mask versus a facemask in preterm infants needing positive pressure ventilation.
General- To compare physical activity levels of pediatric patient subjects with healthy control subjects.- To compare mean heart rate and variation in heart rate during the day of patients and healthy controls.- To compare sleep duration of patients…
- To determine a mean recovery period for patients admitted with pneumonia, bronchiolitis, preschool wheezing and asthma by using data obtained during admission and via home-monitoring of a two week period following admission and control period and…
The primary aim of the study is to compare the effect of PRO symptom monitoring with standard care on QoL both during and up to 1 year after treatment. Secondary aims are studying the effect of PRO symptom monitoring compared to standard care on the…
1) To collect continuous data2) To extract and describe features, patterns and relationships in the data3) To quantify relationships between vital signs and activity variables or exposure to air pollution4) To identify features, patterns and…
Primary:To compare the number of critical errors made by COPD patients, after a subject has read the respective patient information leaflet(s) (PIL), for each treatment option tested.Secondary:Number of critical errors made after instruction from…
The overall aim of the study is to improve personalized medicine for patients with severe asthma through the investigation of possible immunological mechanisms responsible for non-response or incomplete response to biological treatments.2.1 3TR -…
Remimazolam for long-term sedation during invasive mechanical ventilation in critically ill patients
To elucidate whether a sedation regimen with remimazolam can reduce the ICU length of stay in critically ill patients with renal failure, compared to patients treated with a sedation regimen with midazolam.