13 results
Primary objective:To assess the overall feasibility of undertaking a definitive randomized controlled trial on the effects of tailored inhaler education by the GP/nurse supported by a smart spacer, in primary care treated adults with asthma.…
The goal of this study is to obtain insight into possible differences in macrophage and monocyte populations in uncomplicated pregnancies and pregnancies complicated by FGR.
Collagen barrier membranes are widely used for ridge preservation applications. Once an extraction socket is filled with a bone filler and covered by a collagen membrane, guided bone regeneration (GBR) is observed due to the barrier function of the…
We would like to investigate if use of donor FMT enriched desulfovibrio bacterial strains has a beneficial effect on gut microbiota diversity and subsequent improvement of (diet derived) fructose catabolism and insulin sensitivity in patients with…
To quantify the impact of the use of DeltaScan on patient outcome (duration of admission) in patients with high risk of delirium compared to the currently used delirium screening tools.
The primary research question of the trial is to assess whether foot drop, caused by peroneal nerve entrapment in adult patients* recovers better within 9 months after decompressive surgery compared to prolonged standard conservative treatment. *…
To determine the effectiveness of a decision rule compared to the usual care of GP*s for patients presenting with non-traumatic chest pain in primary care.
The primary objective is to assess the in vivo wear of the two randomized polyethylene insert types N2Vac and X3 10 years after surgery. The secondary objective is to assess the migration and long-term survival of the Triathlon CS Peri-Apatite…
The primary objective of this observational study is:- to determine if patients with Chronic Liver Disease (CLD) mount comparable humoral immune responses to healthy controls at 8-months following SARS-CoV-2 vaccination.Secondary objectives of this…
The primary objective of this study is divided into two steps:Step 1. To investigate the effect of a 26-week (around 6 months) multidomain lifestyle intervention on brain function (working memory, cerebral perfusion) and peripheral immunometabolic…
To test the hypotheses that patients who show severe fatigue after COVID-19 infection exhibit an exaggerated abnormal expression of inflammatory monocyte genes (particularly of the genes involved in pyroptosis, such as IL-1 and IL-6) as compared to…
The objective of this trial is to evaluate the safety and effectiveness of the Amulet device compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy.
Primary Objective(s):1. To study the presence and extend of exercise intolerance in male, female FD patients with classical FD and men with non-classical FD, in different stages of the disease.2. To determine the aetiology of exercise intolerance in…