576 results
To assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer*s disease-causing mutation by determining if treatment with the study drug slows the rate of progression…
To investigate whether perturbation of the left middle temporal gyrus results in immediate adaptation in the right hemisphere, indexed by a shift of alpha-beta oscillatory effects from the left to the right hemisphere.
The main objective of this study is to investigate the effect of cerebellar tDCS on impulsivity in healthy adults.
Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo
We hypothesise that using a continuous subcutaneous glucose monitor during pancreatic surgery, will significantly improve percentage of time spent in glycaemic target range (i.e. glucose ≥ 4 mmol/l and < 10 mmol/l).
Does a Attention Control Training in patients in the experimental group with a PTSD prior to the TAU lead to a better outcome than in patients in the control group with a PTSD who have received a sham (fake) training prior to the TAU ? This is also…
This study aims to establish a plasmakinetic profile of GABA from tomatoes in healthy men and compare it to the kinetic profile of GABA from a supplement. In addition, the effects of glutamate (precursor of GABA) on the plasma-time curves of GABA…
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
To determine the safety and tolerability and to assess the PK and performance of VB5-845D-800CW in healthy volunteers and patients
RTX 1*1000 mg compared to a placebo controlled group leads to a higher proportion of patients in glucocorticoid remission at week 21 in newly diagnosed PMR patients fulfilling the Chuang-criteria
A combined tDCS-working memory intervention in healthy military personnel strengthens self-regulation under threat via effects on DLPFC-linked neural activity.
Infant formulae with higher levels of milk fat result in improved microbiota composition as compared to standard formula.
1. Compared to unfortified biscuits (UB), consumption of multiple-micronutrient fortified biscuits five days/week for 26-weeks will improve micronutrient status and vertical growth of female adolescents 2. The timing of intervention (before or after…
To evaluate the effectiveness of two well defined probiotic strains, Lactobacillus paracasei LPc-G110 (CCTCC M 2013691) and Lactobacillus plantarum GOS42 (DSM 32131), in strengthening the oral ecosystem.
Antimicrobial therapeutic clothing are more effective in reducing the severity of atopic dermatitis than non-antimicrobial therapeutic clothing
It is hypothesized that Ziverel tackles esophageal hypersensitivity by protecting the mucosal barrier function.
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis
In this study we will validate nerve excitability threshold tracking, a measurement technique for neuronal excitability. The placebo-controlled mexiletine and lacosamide administration should inform us about the sensitivity of threshold tracking to…
Adjuvant therapy of levamisole to prednisolone prevents relapses in children with a first episode of idiopathic nephrotic syndrome.