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A randomised, double-blind, placebo-controlled trial for establishing safety, tolerability, pharmacokinetics, pharmacodynamics and clinical efficacy of multiple subcutaneous doses of BI 655064 in healthy volunteers and in rheumatoid arthritis patients with prior inadequate response to methotrexate therapy

This study has two parts. The main purpose of Part 2 of this study is to see how safe and effective different doses of BI 655064 are as well as to look at the pharmacokinetics (the amount of medication in your blood) and the pharmacodynamics (the…

Effect of Acupuncture on sedation requirement during Colonoscopy
(EAcCo)

We hypothesize that acupuncture reduces the dosage of sedatives for colonoscopies. We will compare three groups to test our hypothesis. One group will receive verum-acupuncture, another group sham-acupuncture and the third group will be the control…