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A randomised, double-blind, placebo-controlled crossover study to investigate the effect of buprenorphine on fentanyl induced effects on nociceptive thresholds and CNS functioning in opioid tolerant patients.

Primary objectives- To evaluate the effects of buprenorphine on fentanyl induced analgesia using the PainCart test battery in OT patients, when compared to placebo.Secondary objectives- To evaluate the effects of buprenorphine on fentanyl induced…