27 results
Primary Objective: Primary: Gut microbiota (oral and fecal) and nasal microbiota composition in relation to autoimmunity status (antibodies (ANA, ANCA) and HLA subtype) and inflammatory functional assays as well as disease&…
Main objectivesCohort study:To investigate the prognostic implications of skin sodium accumulation for CKD patients.Sodium excretion intervention study:To study the effect of increased renal sodium excretion, with and without …
In this research, we are comparing two distinct physiotherapy treatments as post-operative care following shoulder arthroscopy (Bankart repair). Our aim is to gain a better understanding of how to provide optimal post-operative care for patients…
Main objective is to determine whether nerve excitability can detect drug-induced effects of Riluzole in yet treatment- naïve patients with ALS. Secondary objectives are to determine the correlation between the Riluzole plasma concentration levels…
The primary objective is to show that brain MRI surveillance alone is non-inferior in terms of overall survival (OS) to brain MRI surveillance combined with prophylactic cranial irradiation (PCI) for the treatment of small cell lung cancer (SCLC).
The current study describes the Antisocial High-Risk Cohort (i.e., WP3, a sub-project) of the larger Growing Up Together in Society Project (see appendix A), which has the aim to predict and understand behaviour that negatively affects society:…
Our project aims to investigate cognitive and linguistic deficits in people with SCD, focusing on working memory impairments, deficits of lexical access, and deficits brought on by syntactic complexity. We will integrate clinical linguistic…
The primary objective of the pilot study is to assess the feasibility of a definitive trial to determine the effect of arthroscopic soft tissue stabilization vs. non-surgical treatment on rates of recurrent anterior …
The primary objective of this study is to compare the mean binocular DCIVA at 66 cm under photopic conditions 3 months after cataract surgery, in a series of patients, who previously underwent myopic laser surgery, bilaterally…
To identify the effect of psoriasis and the treatment with biologics on the pre-pregnancy uterine immune environment of psoriasis patients.
Primary Objective: To explore the computations which occur in the brain which occur in visual disorders and determine how these differ from healthy controls. Specifically, we expect that the overall sensitivity (area under the curve) which reflects…
Primary: investigate the (cost-)effectiveness of replacing RFU after THA and TKA at 10 years by COD by comparing the complications and clinical visits between patients with COD versus RFU at 10 years after THA and TKA. Secondary: investigate the…
To investigate the (cost-)effectiveness of COD compared to RFU at 1 year, up to 2 years after THA and TKA.
The primary objective of this project is to evaluate the differences between a wide variety of cardiac disease and healthy volunteers using novel echocardiographic techniques (LV SV-loops, 3D RV beutels and SWI) and relate these to patient…
To study the feasibility and safety of permissive lung–protective ventilation in adult critically ill patients receiving invasive ventilation for acute hypoxemic respiratory failure, and to inform the design of a future randomized clinical trial in…
The objective of this study is to quantify the subjective feeling of knee (in)stability during a stair descent. This results in the following research question:*Is there a relation between the kinematics of the knee joint from people who suffer…
The purpose of the pivotal study is to determine the safety and efficacy of IMPEDE-FX RapidFill for increasing the percentage of subjects with shrinkage of the abdominal aortic aneurysm sac when used as an adjunct to on-label EVAR stent graft…
To evaluate the disease course of diverticulitis in immunocompromised patients to determine a safe and effective treatment strategy.
Our primary objective in this study is to predict treatment outcome for SSRI, CBT, rTMS, esketamine, and ECT in patients with MDD with the use of biomarkers and machine learning using data obtained before a new or follow-up treatment. Our secondary…
The aim of this study is to compare oxycodone and morphine as the first-choice opioid for postoperative pain after orthopedic surgery regarding: The proportion of patients with new long-term opioid use (>6 months). The total proportion of…