39 results
The primary objective of this investigator initiated project is to determine whether the use of the WalkinSense in the production of new fully customized therapeutic footwear for diabetic patients with a history of foot ulceration results in lower…
The aim of this study is to investigate the effect of guided tapering in early pregnancy as compared to continuation of SSRIs during pregnancy. We will study effects on both mother and child with a pragmatic approach.
Main objectives: Establishing the effect of BF as predisposing factor for the development of VGE and hence DCS by using subjects with a restricted range in age and VO2max. Establishing the effect of TC/HDL ratio and FFA as predisposing factors for…
To study the incidence of (mild) acute hyponatremia in ecstasy users at rave parties.
This evaluation research will focus on six elements (1) the technical evaluation of the system (2) the validity and reliability of the system, (3) the succession of the protocol, (4) the effects of the Quiet Care System for the client, the informal…
To investigate in situ a possible effect of 4 different tootpastes on the developement of dental erosion and on the composition of the pellicle.
This study will evaluate the effect of approximately 10 years of pravastatin treatment on IMT in young adults with FH. Furthermore, safety parameters and psychological aspects with respect to early treatment initiation will be investigated.
Objective of this study is the development of a national "best practice guideline on pre and postnatal follow up for prenatally detected abnormalities of the kidney and/or urinary tract". Furthermore, the guidelijne will be evaluated and…
To investigate what the ideal moment to vaccinate would be, early (after 2-6 months) or late (after 9-12 months) after cessation of rituximab. Secondly to study the immune-response to vaccination with influenza virus vaccine after treatment with…
Are overweight or obese patients protected against atherosclerosis when suffering from haemophilia A? Is this association influenced by the severity of haemophilia? When the coagulation activity increases due to obesity (and inflammation), will this…
The aim of this project is to investigate whether a first trimester model of 3D placental volume, 3D power Doppler measurement of the placental vascularization and/ or serum levels of PAPP-A, PlGF, PP-13, PAI, Ang-2, sFlt and SEng can predict early…
To investigate the maintaining factor of mood-congruent memory bias of depression, the circumstances when they occur and the neural correlates of these.
Study the risk of colorectal adenomas in patients detected with duodenal adenomas.
Aim of this study is to address the role of pancreatic ABCA1 dysfunction in humans. We hypothesize that beta cell capacity (insulin production) is reduced in subjects with loss-of-function-mutations in ABCA1.
To determine the contribution of proximal or distal muscle weakness to perturbations of stance induced by posturography.
To determine the effect of probiotics (microbial food supplements) on acquisition rates and colonization prevalence of CC17 ARE in two wards where ARE-colonization is endemic.
Aim of this study is to investigate the effects of oral administration of GTS-21 in healthy volunteers on cytokine release in ex-vivo TLR agonists stimulated whole blood . Pharmacokinetic and pharmacodynamic data will be collected with respect to…
The goal of the study is to find out whether micturition complaints are prevented or reducted by the bladder instillations with Uracyst and secondly if it has a positive effect on painscores and micturition related quality of life.
To examine whether platelet hyperreactivity, as assessed by various platelet activation or function tests, could explain recurrence of cardiovascular events among patients that suffered a first MI.To assess which (combination of) platelet activation…
To demonstrate attenuated ischemia-reperfusion damage in subjects that have become tolerant due to repeated endotoxin administrations.