209 results
The aim of the project is to investigate whether the Nova contributes to cost-effective, client-oriented incontinence care for people with a profound disability, based on a cluster randomized study with a waiting list control group and a pragmatic…
The aim of this study is to obtain answers to the following main questions:1. Are delay discounting, time estimation and PTSD influenced by treatment?2. Do patients differ from healthy controls in delay discounting and/or time estimation ability? In…
The primary objective is to develop algorithms that define digital biomarkers for disease progression in Progressive Supranuclear Palsy patients. The biomarkers, when developed systematically, can eventually serve as primary or secondary clinical…
To contribute to building a sound scientific basis for the regulatory EU institution to set-up occupational exposure limits and related biological limit values, as well as reference values for the general population and to study the impact of the…
Primary objective:Answering the following research questions: Does relaxation (with the help of an instruction and the biofeedback relaxation tool) compared to 'quietly lying down' result in lower activity of the pelvic floor and in a more…
The objectives of this study are: 1) to assess the feasibility, accuracy and efficacy of simultaneous, conventional and micro-electrode mapping using the QDOT catheter to delineate and ablate the functional substrate of post-MI VT compared to…
In this study we will investigate how safe the new compound deramciclane is, when it is given alone and in combination with the existing medication dextromethorphan (Part B), and how well it is tolerated when it is used by healthy elderly…
Primary objective: To investigate whether there are differences in Doppler ultrasound (US) parameters measured during the routine 13-week scan between pregnancies complicated by uteroplacental insufficiency (UPI) and pregnancies not complicated by…
To assess the effects of (reduced) volume overload on the left atrial wall texture (presence, amount and location of atrial fibrosis) and associated geometry and function in patients with MVI, prior to and after elective mitral valve repair surgery.
The main purpose of this study is to investigate the effect of ASTX660 on how quickly and to what extent quinidine and fexofenadine are absorbed, distributed, broken down and eliminated from the body. Quinidine and fexofenadine have been chosen…
The objective of this study is to elucidate unique and shared impairments across a broad range of social cognition tasks (at the behavioral, neuropsychological, and neurophysiological level by means of EEG recordings) related to subdimensions of…
Primary Objective:To evaluate the safety and tolerability of FL-101 as monotherapy.Timepoint of evaluation of primary objective: From first dose to 3 months after surgerySecondary Efficacy Objectives1. Cohort 1: To evaluate the activity of FL-101…
In the coming months, immunocompromised patients treated in our hospital will be requested to undergo vaccination if they comply with the National Institute for Public Health guidelines. For all subgroups, it is of utmost importance to assess the…
This study aims to investigate the progression-free survival (PFS) according to RECIST 1.1 criteria on matched targeted therapy by STA-analysis (PFS2) in comparison to the PFS recorded on the therapy administered immediately prior to enrolment (PFS1…
This study will be the first controlled study specifically investigating the effect of EMDR on FM pain and additional physical symptoms.
The primary objective is to see whether a live music intervention can significantly lower perceived postoperative pain compared to recorded music intervention and do-nothing control. The secondary objective is to explore neuroinflammatory…
Primary* To estimate the effect of NME combination therapies on inducing a functional cure over the control arm.Secondary * To characterize the efficacy profile of NME combination therapies.* To characterize the PD profile of NME combination…
Primary objective:Investigate if a trained immunity profile in innate immune cells might be a mechanism of HIV elite control.Secondary objectives:1. Determine the immune phenotypes that distinguishes family members of HIV elite controllers from…
Evaluation of longterm clinical and radiological results.
To study the feasibility and effects of EMDR on FCR.