248 results
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
To compare the level of the sIL-2R between patients who are referred to the Center for Pain Medicine with a suspicion of CRPS but do not fulfill the new IASP Clinical Diagnostic Criteria for CRPS and those who do fulfill the new IASP Clinical…
Calibration of the mitochondrial oxygen tension technique in the human skin
This project aims to determine the validity of a home-based continuous bradykinesia assessment using free typing behaviour analysis. Secondarily, we aim to capture the presence of sequence effect in Parkinson's Disease patients using a computer…
2.1 Primary objectives2.1.1 Cross-sectional part• Technical evaluation of the functional and structural outcome measures to support a biomarker qualification by regulatory authorities and payers. 2.1.2 Longitudinal part • Assessment of prognostic…
Optimise post PVI management using ambulant continuous patient-driven eHealth monitoring after catheter ablation in the treatment of atrial fibrillation.Primary Objective:1) Determine the effect of eHealth on clinical management, outcomes and…
Gaining an objective insight in muscle fatigue during exercise for patients with FSHD by 1. comparing the timing of change in sEMG amplitude and sEMG median frequency, to gas exchange variables, heart rate, work load and blood lactate levels during…
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
The aim of this pilot study is to assess the effect of low intensity mastication training in patients with a mitochondrial disease on masticatory performance, efficacy, endurance, bite force and the feasibility of this training .
To investigate associations between IBD severity, ASCA titer, microbiota composition and C. albicans strains present in feces.
The main purpose of this study is to find out whether EMDR is a safe and effective treatment to reduce the symptoms of PTSD in people with mild intellectual disability and borderline intellectual functioning. In addition, it is expected to reduce…
The purpose of this study is to investigate how safe the new compound M254 is and how well it is tolerated when it is administered to healthy volunteers and patients with immune thrombocytopenia (ITP). M254 has not been administered to humans before…
The aim of this study is to develop a safe and fast MRI protocol for the imaging of neonatal and pediatric BPD patients. This METC application addresses the first part of the MRI- BPD project: *Ventilation, Inflammation, perfusion and structure in…
The main objective of this study is:* To determine the effect of inpatient self-administration of medication on the number of medication administration errors during hospitalization*The secondary objectives of this study are:* To determine the…
The objectives of this study are to investigate the correlation of the handscan measurement with DAS28 and ultrasound measurement of the hands and to investigate the responsiveness to therapy of the handscan device. Also the correlation between the…
Primary Objective: To evaluate the feasibility and test-retest reliability of the Swallowing Performance EATing and drinking (SPEAT)-test in assessing swallowing function. Secondary Objectives: - To explore the intra- and inter-rater reliability and…
General- To compare physical activity levels of pediatric patient subjects with healthy control subjects.- To compare mean heart rate and variation in heart rate during the day of patients and healthy controls.- To compare sleep duration of patients…
The primary purpose of this study is to report the functional performance after Ligamys surgery. The expactation is that the Ligamys method will achieve the 90% LSI benchmark at the hoptests and less than 9% difference with the control group. The…