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The optimal treatment strategy for complex appendicitis in the pediatric population

Subgroup 1 (complex appendicitis without mass and/or abscess formation): LA is associated with reduced superficial site infections, shorter length of stay, less costs, less pain, and better hr-QoL, compared with OA without compromising overall…

Direct or indirect placement of fixed braces

The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…

DISCOVER study: Detecting Increased Susceptibility for Cancer in relatives by Offering genetic Variant Evaluation as Regular health care: prostate cancer

Mainstreaming of germline genetic tests in regular healthcare is feasible for healthcare professionals and acceptable for both patients and healthcare professionals

A study on the cost-effectiveness of risk scoring models for the discrimination between benign or malignant ovarian tumors

Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…