102 results
The main objective of this study is to detect potential biomarkers for the differentiation of PD and DLB and the differentiation of PD subtypes by using neuroimaging.
We aim to extend our recent work on fundamental mechanisms that underlie automatic influences of reward on attention to clinical populations that suffer from reduced and excessive reward-driven behaviours. That is, we will investigate whether…
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
The main objective of this study is to determine the language representation in the brain of children with SLI and 22q11DS.
The primary objective is to study if quantitative (3- and 7-Tesla) MRI protocols (MRI perfusion, diffusion tensor imaging (DTI), and chemical shift imaging (CSI)) are able to detect phenotype conversion earlier than conventional MRI. Results will be…
The primary objective is to assess neuropsychological function in X-ALD patients without active cerebral demyelinating disease. Data of minors will be compared to matched healthy controls. Data of adults will be compared to reference values. The…
Various brain areas play a crucial role in both pain and cognition, supporting the existence of a close relationship between pain and cognition. Consequently, it is important to examine whether pain experience changes at the moment the patient shows…
This study should show whether patients with focal BG lesions are impaired in changing the threshold between deliberate fast or accurate conditions, and between conditions with and without prior information. Also, it should show that patients with a…
Obtaining fundamental insight into sensorimotor integration in Parkinson's disease, targeted on (i) the relationship between cognitive deficits and prosodic anomalies, and (ii) the effect of music on the motor aspects of speech production.
The primary objective of this study is to detect statistically significant differences between the most severely affected PD subtype and controls on 3T imaging parameters.
In this study we want to investigate if relaxation time (RT) measured by handgrip myometry and muscle- elastography is a reliable outcome measurement for the quantification of myotonia in NDM patients. Mean RT values en standard deviations of NDM…
We want to gain more fundament insight in disturbed sensorimotor integration in PD, particularly with regard to the impact of visual stimuli on the cerebral organization underlying gait control. Such knowledge provides arguments for targeted patient…
(1) Evaluate whether stroke patients differ from healthy controls on the experience and the course of subjective cognitive complaints during the first two years after stroke;(2) Evaluate potential predictors for cognitive complaints during the first…
The aim of the current study is to identify couplings of muscle activation patterns (muscle synergies) in reaching movements in stroke patients. Insight in the motor control of stroke patients can contribute to improve the disabled arm functioning…
The primary objective of this pilot study is to assess the prevalence of visual field defects in formerly eclamptic women. The secondary objective is to compare the vision-related quality of life between formerly eclamptic and normotensive parous…
The aim of the present study is to investigate the reproducibility of upper extremity strength measurements in children with CP. The following strength measurement instruments will be studied: Hand Held Dynamometry (HHD), pinch- and grip strength…
The main objective of this study is to characterize the features and the extent of extracerebellar structural pathology in SCA3 and SCA6 patients. Secondary objectives are:- To explore the sensitivity of DWI and other imaging modalities in detecting…
1. To determine the reproducibility of the ECWT and the 6MWT to assess the physical strain of walking in patients with PPS and in healthy control subjects.2. To evaluate the one-year course of the physical strain of walking among patients with PPS…
Primary Objective: To determine the characteristics of the short-latency muscle response (SLR) in patients with Parkinson*s disease, in comparison to age-matched healthy controls.Secondary Objective(s): To correlate the characteristics of the SLR…
We aim to determine the difference in uni- and bimanual coordination between young adults, older adults and MS patients. Additionally we want to determine the relation between the different measures of cortical inhibition and task performance.