11 results
Our interest is to gain a better understanding about cognitive complaints, mood and fatigue in relation to cognitive deficit in adults 30 to 60 years of age after a first cardiac event.
We aim to validate MRS with a cholinergic challenge as method to investigate muscarinic M1 receptor functioning. To investigate the relationship between the response to a muscarinic receptor antagonist with biperiden phMRI and [123I]IDEX SPECT…
Examine how unexpected reward and unexpected punishment affect working memory, that is, the ability to maintain information across time, update task-relevant information and ignore task-irrelevant information.Determine the extent to which…
In our recent studies we found indications of the existence of particular cognitive deficits as well as memory impairments following different regiments of cytostatic agents. Together with the indications form our animal studies of a potential…
In our recent studies we found indications of the existence of particular cognitive deficits as well as memory impairments following different regiments of cytostatic agents. Together with the indications form our animal studies of a potential…
The primary objective of this study is to determine the prevalence of white matter lesions and subjective/objective neurocognitive functioning in women several years after pregnancy compared to nulliparous women The secondary objective is to…
Cytotoxic treatment may lead to long-lasting brain damage that can result in persistent cognitive changes and accelerated cognitive decline at an older age. The proposed study will investigate whether chemotherapy causes brain changes different from…
In our own recent studies we found indications of the existence of particular executive functioning deficits as well as memory impairments following different regimens of cytotoxic agents. Together with the indication from our animal study of a…
The current study aims to further our understanding of the relationship between baseline measures - such as impulsivity, working memory and social support - and the effects of enhancing dopamine (via methylphenidate administration) across a wide…
As only a subgroup of breast cancer patients experience long-term cognitive decline after adjuvant chemotherapy, it is critical to identify risk factors for this decline. Some risk factor like higher age, lower cognitive reserve (either defined as…
To determine the difference in change over time of cognitive function and brain magnetic resonance imaging (MRI) measurements between breast cancer survivors and cancer-free individuals.