25 results
The aim of this study is primarily to investigate the effects of a withdrawal intervention on measures of driving performance in a clinical population that uses benzodiazepines, Z-hypnotics, or opioid analgesics chronically. As a secondary objective…
The aim of this study is to investigate the effect of guided tapering in early pregnancy as compared to continuation of SSRIs during pregnancy. We will study effects on both mother and child with a pragmatic approach.
1) To investigate the impact of keeping/loosing diabetes on quality of life and psychological well-being in a group of (morbidly) obese patients who underwent bariatric surgery, and 2) To explore whether we can predict postoperative quality of life…
Our primary aim is to tackle the factors of frailty in an early phase, which is possible in elective planned surgery. We hypothesise that optimal preparation, starting 5 weeks before surgery, will reduce the incidence of delirium from 15 % to 7.5…
We want to identify perception biases in bipolar patients with both depressive and hypomanic mood symptoms.
Primary:-To assess whether the genetic architecture of this severe SCZ phenotype differs from the broad DSM-based SCZ phenotypeSecondary:-To detect genetic associations with the current severe SCZ phenotype (case-control comparison)-To unravel…
The main objectives of the trial are* To develop innovative evidence*based, feasible, effective and sustainable nutritional strategies for the prevention of depression in EU citizens.* To establish the feasibility and effectiveness of nutritional…
Research Goals: During the pre-study several clues indicated that hunger isnot increased when tubefeeding is administered. This couldpoint to a lower ghrelin production during tubefeeding,indicating that tubefeeding is the next step in…
The aim of the study is to evaluate the effectiveness of FRIENDS for Life as an indicated school-based prevention programme for children with early or mild signs of anxiety or depression.
The primary objective of the study is to relate depression and anxiety in CHF patients receiving an ICD to the occurrence of ventricular tachyarrhythmias. Secondary objectives of the study are:Assessment of the effects of depression and anxiety on…
To investigate the maintaining factor of mood-congruent memory bias of depression, the circumstances when they occur and the neural correlates of these.
The aim of our study was to examine the effects of the life review therapy on depressive symptoms and feelings of loneliness in older adults living in nursing.
The evaluation of a group therapy for patients with depressive symptoms after stroke - a pilot study
The objective of the study is to investigate the effect of the *Coping with depressive symptoms after stroke* course on depressive symptoms and quality of life in a waiting list controlled study.
Link inter-individual differences in light sensitivity (measured by melatonin suppression) to molecular pathways in primary fibroblasts in SAD patients and healthy controls and with light therapy succes in SAD patients and with gene variation in two…
The purpose of the study is to conduct a randomized controlled trial with the self-help intervention *Voluit leven* for adults with mild to moderate psychological distress. The research question is: What are the effects of the preventive self-help…
The present research aims to evaluate the effectiveness of a culturally adapted, guided and CBT-based online intervention for Turkish speaking migrants presenting suicidal ideation.
The first main objective of this study is 1a. To examine whether striatal [18F]DOPA influx (Ki) values in non-psychotic individuals with ASD are positively related with the total score on the UCLA Loneliness Scale. The second main objective of this…
The objective is to investigate the effectiveness of an Internet-based self-help intervention for people with mild symptoms of anxiety and/or depression. This intervention will be offered with and without guidance and will be compared to usual care…
Primary: To assess whether the genetic architecture of this severe SCZ phenotype differs from the broad DSM-based SCZ phenotype.To predict response and side effects after clozapine intakeSecondary:1. To detect genetic associations with the current…
In the current study, the feasibility, acceptability and effectivity of a new add-on early intervention program for individuals at risk for the development of bipolar disorder is evaluated. This intervention program entails psycho-education, light…