41 results
The aim of the study is to test the hypothesis that susceptibility to and severity of certain infectious and inflammatory diseases can be explained by the interaction between the genome, microbiome and immunological responses: i.e. presence of…
Primary Objectives The main objective of this project is to evaluate the long-term disease burden in meningioma patients. More specifically, we will evaluate: 1) the level of cognitive functioning and HRQoL in meningioma patients at least 5 years…
To compare the protein profile of Barrett*s mucosa with and without early neoplasia in ER specimens in epithelial and stroma aiming to identify a biomarker indicating presence of early neoplasia in BE.
1 To examine the differences in mindfulness between cancer patients and healthy references.2 To examine possible correlates of mindfulness, i.e. factors that may enhance or deplete mindfulness.3 To examine the relationship between mindfulness and…
The aim of this study is to validate known, and identify novel allelic variants which may play a role in the risk of cisplatin-induced ototoxicity in a substantial international cohort of children diagnosed with cancer.
To characterize the interaction between the genetic background, the microbiome, and the immune responses in patients with diabetes type 1, both cross-sectional and over time, and to identify the disturbances in this interaction.
We propose to investigate the health related quality of life (HRQoL) in childhood survivors of refractory GvHD who have been treated with mesenchymal stem cell transfusions. This will be a multi center study involving the Division of Clinical…
The main objective of this study is to examine the incidence of psychosocial needs, anxiety and depressive symptoms at each time point, and to identify risk factors for worse short-term Quality of Life (QOL) in lung cancer patients and their…
The objective of this study is to adapt and pilot an existing psychological intervention program (SCCIP-ND, mentioned above) to alleviate anxiety and distress and to prevent PTSS in parents of pediatric patients who are receiving stem cell…
In this study we investigate the influence of the tyrosine kinase inhibitors sunitinib and sorafenib, on the normal humoral and cellular immune reponse to influenza vaccination in patients with metastases of renal cell carcinoma or a GIST.
The aim of our study is to assess the prevalence of cardiac dysfunction and undiagnosed heart failure in women registered in general practice with a history of breast cancer who received chemotherapy and / or radiotherapy as compared to a matched…
The primary objective of this study is to determine the impact of a diagnosis and type of treatment of cancer, ageing and their interaction on wellbeing of older cancer patients. Furthermore, we aim to determine the different psychosocial…
The overall aim of this study is to examine, in adult female CCS in the Netherlands, the effects of treatment in general, and the effects of different types of treatment, doses of drugs, radiation sites and doses, and age at time of treatment, on: 1…
To study the spread of STI among heterosexual males and females (heterosexuals) in Amsterdam in order to provide information for building evidence-based prevention strategies and to evaluate existing control programs. Three substudies are part of…
With this information we hope to be able provide ex-patients with more detailed information about late effects of treatment. Also it is a very important step towards ajusting current treatment protocol to prevent late effects as much as possible.
Our objective is to test the feasibility and preliminary effects of a web-based patient portal containing a survivorship care plan, online questionnaires for symptoms and HRQL with personalized feedback and a physical activity support programme that…
Primary Objective: To investigate the nature, prevalence, and duration of taste and smell changes in patients with disseminated testicular cancer treated with cisplatin based chemotherapy (BEP or EP).Secondary Objective(s): -To explore the short-…
To study HPA axis regulation and sympathetic nervous system activity in survivors of childhood ALL during relaxation and during stress.
This research aims to assess the effect ofn completing an ACA-task on decision-making regarding short-course pre-operative radiotherapy in the treatment of rectal cancer in clinical practice.