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Effects of a butyrate enema on systemic concentrations of short chain fatty acids

In the present study the effects of the colonic administration of butyrate on portal, hepatic, mesenteric venous and arterial SCFA concentrations will be studied in patients undergoing major upper abdominal surgery. The aim is to clarify the…

Pre-operative Administration of Anti-EGFR Monoclonal Antibodies (cetuximab) for the Eradication of Circulating Tumor Cells in Patients Undergoing Curative Treatment of Colorectal Liver Metastases; a dose finding study

The main objective of this study is to determine whether a single neoadjuvant gift of anti-EGFR mAb, administered 48 hours prior to local treatment of colorectal liver metastases, reduces the number of CTCs. Secondary endpoints are determination of…

In vitro potency of clinically used antiplatelet drugs in patients with Metabolic dysfunction Associated Fatty Liver Disease

To compare the in vitro potency of commonly used antiplatelet drugs in the blood of patients with various stages of fibrosis due to MAFLD, compared to that in blood of individuals without underlying liver disease.

COvid-19 vaccination and Biomarkers in cirrhosis And post-Liver Transplantation

The primary objective of this observational study is:- to determine if patients with Chronic Liver Disease (CLD) mount comparable humoral immune responses to healthy controls at 8-months following SARS-CoV-2 vaccination.Secondary objectives of this…

Preoperative pREhabilitation in patients planned for LIVER Transplantation

The primary objective is to determine the feasibility of a semi-supervised homebased prehabilitation program for patients to be waitlisted for LT. The secondary objectives are to assess the effectiveness of this program and possible improvements of…