17 results
To investigate whether an interactive internet-based intervention strategy targeting vascular and lifestyle-related risk factors can lead to improvement of cardiovascular risk profile and prevention of cardiovascular disease and whether this in turn…
The aim of Prevent CardioKids is to evaluate to what extend disturbed vascular function markers are present in children of different weight categories and whether these are age dependent. Also differences * and relationships between * vascular…
a. To study whether a specific set of biomarkers is associated with PE with DVb. To study whether a specific set of biomarkers is predictive of PE with DV.
The primary purpose of this study is to determine the relation between a physically active lifestyle and the primary and secondary prevention of diseases and death.Using an online questionnaire, we will approach all civilian participants of the…
The aim of this study is to evaluate the efficacy, safety, compliance and tolerability of 15 years of pravastatin therapy initiated during childhood in young adult FH patients.
Primary Objective: comparing hemodynamic stability provided by titration of esmolol in addition to standard perioperative care including low-dose metoprolol to placebo and standard care.Secondary Objective(s): -comparing the incidence of…
This study will evaluate the effect of approximately 10 years of pravastatin treatment on IMT in young adults with FH. Furthermore, safety parameters and psychological aspects with respect to early treatment initiation will be investigated.
Aim of the study is to determine the microvascular function in type 1 diabetes patients with concomitant celiac disease
The primary aim of the proposed study is to assess whether stenting for symptomatic vertebral artery stenosis >= 50% is feasible and safe. A secondary aim is to assess the rate of new vascular events in the territory of the vertebrobasilar…
Our objective is to assess whether patients with SM compared to controls have more advanced atherosclerosis assessed by carotid intima-media thickness (C-IMT) and carotid plaques and have a more adverse cardiovascular risk profile.
1 Assessment whether using a nerve-sparing exposure of the aortoiliac tract during vascular reconstruction will lead to a neurophysiologically intact sympathetic pathway to the intra-pelvic organs and thus to an intact postoperative function.2…
Are overweight or obese patients protected against atherosclerosis when suffering from haemophilia A? Is this association influenced by the severity of haemophilia? When the coagulation activity increases due to obesity (and inflammation), will this…
Are AGEs, as a predictor of increased risk for cardiometabolic syndrome, increased in shift workers?
The aim of this study is to investigate skin AGEs, as a predictor of increased risk for cardiometabolic syndrome, in a shift work population as compared to non-shift workers to assess its potential as an early assessment of the actual risk for…
Our research aim is fourfold:1) We aim to assess the effect of hypertension on functional and structural markers of the brain using 3 tesla (T) and 7T MRI in patients who are temporary drug naïve and will be switched-on to medication as part of…
The primary goals of this project are to 1) evaluate the effectiveness, 2) identify effective elements and 3) find successful implementation factors of an integrated group-based lifestyle intervention programme in primary care.
This study is aimed at understanding status and future cardiovascular disease (CVD) risk in UC outpatients in remission undergoing different anti-inflammatory therapeutic regimens (tofacitinib (a JAK1 - inhibitor), anti-TNF (infliximab or adalimumab…
Primary Objective: Investigate the difference in composite endpoint MACE, major amputation, or target vessel revascularization in PAD Fontaine II patients with and without antiplatelet resistance as measured by a. VerifyNow b. Genetic testing of…