109 results
The objective of this study is to investigate if CEC are elevated in SCD (and if they could therefore serve as a potential tool for assessing SCD activity), and what the relation of CEC is to the patients medical history and to specific laboratory…
Identifying the genotype-phenotype-imaging correlates in GBA mutation carriers with and without Parkinson*s disease using functional and structural magnetic resonance imaging (MRI).
a) To evaluate whether PAPP-A2 and inhibin A could be used as biomarkers for preeclampsia and preeclampsia-related outcome in twin pregnancies. To achieve this objective, we will first assess:- Whether PAPP-A2 and inhibin A levels are increased in…
To assess the effectivity and feasibility of HCV RNA self-testing in reducing the time to diagnosis of HCV re-infection in MSM previously cured of an HCV infection, compared to the current diagnostic standard of care. To evaluate whether the uptake…
Develop and implement a new functional MRI protocol for function mapping in young children.
The main objective of this study is to create and validate subject-specific models of the human neuromuscular system capable of estimating neuro-mechanical activity in vivo in healthy, post-stroke and SCI individuals. In addition, we want to prove…
- To establish the relationship between the use of deep neuromuscular blockade (NMB) with low pressure pneumoperitoneum (PNP) and the quality of recovery after RARP.- To establish the relationship between the use of deep neuromuscular blockade (NMB…
The objectives of this study are: 1) to assess the feasibility, accuracy and efficacy of simultaneous, conventional and micro-electrode mapping using the QDOT catheter to delineate and ablate the functional substrate of post-MI VT compared to…
The objective of this study is to determine whether contralesional cTBS treatment modulates the interhemispheric imbalance in excitability or local or transcallosal inhibitory processes in the motor network of a population of stroke patients…
The primary objective is to characterize the programming effects of Boston Scientific Vercise* PC System using the Deep Brain Stimulation Directional Lead for bilateral subthalamic nucleus DBS for the treatment of Parkinson*s disease in acute and…
This study investigates the impact of a goal directed nutritional support protocol on sarcopenia in oncological patients undergoing an esophagectomy and secondary the incidence of anastomotic leakage and pneumonia, surgical infection and lenght of…
Primary questionAre changes in vigilance in type 1 and 2 narcolepsy, idiopathic hypersomnia and epilepsy with only nocturnal seizures reflected in differences in the responsiveness of the pupils to light as measured by pupillometry (PIPR) versus…
Objective: Since the inflammatory reaction plays an important role in wound healing problems and scar formation the main goal of this project is to unravel different inflammatory mechanisms involved. • Explore relationships between local and…
Primary objective is to investigate the effectiveness of ADAPT vs TAU on family functioning of veteran families as reported by the veteran. Secondary objective is to investigate the effectiveness of ADAPT versus TAU on family functioning as reported…
1) To investigate the effectiveness of Multi-family therapy (MFT) versus individual oriented treatment as usual (TAU) on end-of-treatment family functioning of veteran families, as reported by the veteran. TAU consists of supportive counselling or…
To assess the long-term safety and tolerability of 35 mg and 70 mg RVT-101 in subjects with DLB
To determine ex vivo neutrophil functions following exposure to therapeutic antibodies targeting inhibitory receptors expressed by neutrophils from RSV bronchiolitis patients. A secondary aim is to study soluble inhibitory receptors (such as LAIR-1…
The aim of this study is to investigate how many patients with an early and/or chronic psychotic disorder reach personal recovery during follow-up and which determinants and processes influence personal, clinical, functional and societal recovery…
To obtain sex-specific biomarkers, based on pathogenesis of microvascular disease, that improve the early diagnosis of diastolic dysfunction and HFPEF. These biomarkers come from innovative sources such as circulating endothelial cells,…
Objectives for the Randomized Observe-Blinded Phase:Primary Objectives:Primary Efficacy Objective• To demonstrate the efficacy of a 2-dose schedule of CVnCoV in the prevention of first episodes of virologically-confirmed cases of COVID-19 of any…