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CALCification as an early marker of vasculopathy and organ involvement in Systemic Sclerosis

1. To assess serum calcification propensity (T50) in SSc patients compared with healthy age and gender-matched controls; 2. To assess serum T50 in SSc patients with overt calcinosis cutis as compared to age and gender-matched SSc patients without; 3…

CHECkUP: Control in the Hospital by Extensive Clinical rules
for Unplanned hospitalisations in elderly Patients.

BACKGROUND/OBJECTIVEHospital readmissions are an indicator of quality of care. To assess whether medication reviews with an extensive set of clinicalrules can help to reduce the number of readmissions, we plan to perform a randomised, multicenter,…

A Phase II, prospective, intra-patient randomised controlled, multicentre study to evaluate the safety and efficacy of an autologous bio-engineered dermo-epidermal skin substitute (EHSG-KF) for the treatment of full thickness skin defects in adults and children in comparison to autologous split-thickness skin grafts (STSG)

This study has been transitioned to CTIS with ID 2024-512190-27-00 check the CTIS register for the current data. To evaluate the efficacy and safety of EHSG-KF in comparison to STSG (unmeshed or meshed up to 1:3) in adults and children with large…