172 results
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
Calibration of the mitochondrial oxygen tension technique in the human skin
This project aims to determine the validity of a home-based continuous bradykinesia assessment using free typing behaviour analysis. Secondarily, we aim to capture the presence of sequence effect in Parkinson's Disease patients using a computer…
Gaining an objective insight in muscle fatigue during exercise for patients with FSHD by 1. comparing the timing of change in sEMG amplitude and sEMG median frequency, to gas exchange variables, heart rate, work load and blood lactate levels during…
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
The aim of this pilot study is to assess the effect of low intensity mastication training in patients with a mitochondrial disease on masticatory performance, efficacy, endurance, bite force and the feasibility of this training .
To investigate associations between IBD severity, ASCA titer, microbiota composition and C. albicans strains present in feces.
The main purpose of this study is to find out whether EMDR is a safe and effective treatment to reduce the symptoms of PTSD in people with mild intellectual disability and borderline intellectual functioning. In addition, it is expected to reduce…
The aim of this study is to develop a safe and fast MRI protocol for the imaging of neonatal and pediatric BPD patients. This METC application addresses the first part of the MRI- BPD project: *Ventilation, Inflammation, perfusion and structure in…
The main objective of this study is:* To determine the effect of inpatient self-administration of medication on the number of medication administration errors during hospitalization*The secondary objectives of this study are:* To determine the…
Primary Objective: To evaluate the feasibility and test-retest reliability of the Swallowing Performance EATing and drinking (SPEAT)-test in assessing swallowing function. Secondary Objectives: - To explore the intra- and inter-rater reliability and…
We aim to clinically establish that the subscapularis is crucial for glenohumeral stability in two work packages. In work package 1, we will test the hypotheses that at baseline patients with degenerative subscapularis tears: 1) advocate…
The aim of the proposed study is to screen for (pre)DM, an increased 10-year-risk of ASCVD, MetS and a high risk of OSAS in subjects with and without periodontitis. Consequently, the dental office will be evaluated as a suitable location for early…
CENTRAL OBJECTIVETo investigate whether the use of CRP POCT results in a reduction in antibiotic prescribing for NH residents with suspected LRTl, without any negative consequences for patient recovery.SECONDARY OBJECTIVES1) To explore potential…
The primary objective of the MANTA-study is to investigate MEG-based network topology and 'activity dependent degeneration' as mechanisms in the stereotypical spread of tau pathology (18F-AV1451 retention) in preclinical and clinical…
1. To study reproducibility of a qualitative scale for abnormality of brachial plexus MRI.2. To study usefulness of quantification of nerve size using maximum intensity projection techniques (MIP) , and compare results with HRUS of the brachial…
We aim at investigating the interplay between DUX4 and inflammation in FSHD combining MRI imaging, histology, gene and cytokine expression.
To obtain insight into the occurrence and nature of potential problems underlying difficult-to-treat RA and into its clinical burden, that will eventually be used to improve the management approach for difficult-to-treat RA.