3565 results
To assess microglial activation in first episode patients with psychotic symptoms and first episode medication naïve patients with psychotic symptoms compared to healthy controls using the positron emission tomography (PET) tracer [11C]-R-PK11195.
To investigate whether children with OI who use a wheelchair (for long distances) can reliably perform a valid shuttle ride test in order to assess the levels of health-related fitness in this group.
Theoretically the anatomical reconstruction technique should give better results in rotational stability due to a more anatomical placement of the ACL-graft. Though it is difficult to test this correlating to functional outcome, because in current…
Quantify inflammatory response (through IL-8 production) of bronchial (both commercial available cells and cultivated brushed infant cells) when exposing these to gastric juice from: hospitalized Infants, before and during PPI treatment and age…
Part I of the study: I) to determine if one or a batch of aging marker(s) is/are associated with the presence of objectively diagnosed COPD related co-morbidity (muscle wasting, osteoporosis, cardiovascular risk, glucose intolerance, renal failure,…
Primary Objectives: 1.1: To evaluate the feasibility of determining sensory thresholds in patients with JIA using QST.1.2: To examine which sensory modalities are particularly affected in JIA patients compared to healthy controls in order to define…
The main objective of this study is to compare DTI findings of PPS patients with those of healthy controls. Secondary objective of this study is to correlate DTI findings with clinical data such as isometric muscle strength. Third objective is to…
The main goal of the study is to characterize the perception of reflexives and pronouns in normally developing normal-hearing, hearing-impaired and cochlear implanted children. The proposed project consists of a longitudinal study spreading over 5…
We aim to determine an association between the presence of complement binding anti-paternal HLA-C antibodies and preeclampsia.
In recent years, we have identified a Dutch family and performed a large number of studies which have helped us gain insight into the disorder. (MEC protocols 02/223 and 03/140, Dissertation Van Rootselaar, 2006). We want to call on family members…
The main objective is to evaluate the facial function in patients with UCM. In this study we set out to evaluate how the facial deformity influences the self-esteem and self-evaluation i.e. satisfaction of the patients and what the valence is of…
As only a subgroup of breast cancer patients experience long-term cognitive decline after adjuvant chemotherapy, it is critical to identify risk factors for this decline. Some risk factor like higher age, lower cognitive reserve (either defined as…
Primary: to evaluate and compare the efficacy of:1) PDL treatment followed by topical sirolimus application after Er:Yag laser ablation of the stratum corneum in PWS 2) PDL treatment followed by topical sirolimus application without Er:Yag laser…
To determine the relationship between phenotypic, genetic and biochemical features of AD. , Relevant bimarkers of the skin barrier function including the levels of NMFs, inflammatory mediators (e.g. IL-1 cytokines), SC lipids and serine proteases…
Primary Objective: - Antibodies to the hepatitis B surface antigen (anti-HBs) levels 30 days after the last hepatitis B vaccine dose (11 months) in children from IBD mothers treated with anti-TNF compared to children from IBD mothers not treated…
- Can early Botox-injections in the bladder of patients with meningomyelocèle (MMC) prevent deterioration of the bladder and renal function?- Can early Botox-injections in the bladder of patients with meningomyelocèle (MMC) decrease the need for an…
This study addresses the following three questions:1. How do fear memories change over time?2. How is the context of fear coded in the brain?3. How can the process of excessive strengthening of fear memory be disrupted
The main objective is to investigate if the sensation of children with an upper OBPL is diminished. Both children that were treated conservatively as children that were surgically treated with nerve surgery in early infancy.The primary research…
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
To evaluate the clinical usefulness of the VU-AMS in pediatric cardiology.To validate and improve the measures of stroke volume from the VU-AMS device in a clinical population. VU-AMS stroke volume measures will be compared with stroke volume…