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Bioavailability of Zinc from milk and rice using a stable isotope method

Study I: To assess the bioavailability of Zinc from full cream UHT milk, fortified full cream UHT milk, a supplement, and raw milk.Study II: To assess the potential enhancing effect of milk on Zn absorption from intrinsically labelled rice (as a…

Influence of an acidic beverage on the absorption of erlotinib

To determine the influence of the acidic beverage Coca-Cola, concomitantly taken with erlotinib (with or without a PPI), on erlotinib plasma pharmacokinetics compared to erlotinib concomitantly taken with water in cancer patients.

A randomized, open label balanced two period, two-treatment, two-sequence crossover study to evaluate the effect of food on the pharmacokinetics of buspirone after a single oral administration of Lybridos in healthy female subjects

Primary objective1. To determine the effect of food on the pharmacokinetics of buspirone administered as the Lybridos formulationSecondary objective1. To evaluate the safety and tolerability of a single dose of Lybridos under fasted and fed…

A randomized, cross-over, dose-response trial of tyrosine and its effect on working memory in healthy elderly and young people

The primary objective is to choose the dose (100, 150 or 200 mg/kg body weight) of tyrosine that shows the highest increase in plasma tyrosine concentration, based on comparison of the dose-response curves, in elderly. These dose-response curves…

The Dynamics Study:
Influence of NaCl intake on Microcirculation and Immune sytem

In this study we aim to elucidate effects of dietary sodium intake on:1. Microcirculation by studying the capillary network during high and low sodium conditions.2. Adaptive and innate immune system by studying circulating T-lymphocyte…

Comparing patient's preference of dorsal column stimulation versus dorsal root ganglion stimulation in patients with complex regional pain syndrome confined to the knee

Dorsal column stimulation and dorsal root ganglion stimulation are both proven to be effective as treatment for chronic, neuropathic pain. We want to compare patients preference of stimulation type in patients with chronic, neuropathic pain due to…

A randomized, open label balanced two period, two-treatment, two-sequence crossover study to evaluate the effect of food on the pharmacokinetics of sildenafil after a single oral administration of Lybrido in healthy female subjects

Primary objective1. To determine the effect of food on the pharmacokinetics of sildenafil administered as the Lybrido formulation2. To determine whether >90% of the testosterone content is released after maximally 90 seconds after sublingual…