38 results
This study is aimed to determine the efficacy of varenicline in reducing EDS in PD patients.
Primary Objective: To study the differences between EB post oxygen-dive, post air-dive (control), dry-dive (recompression chamber) and pre-dive (baseline).1. Will an exposure to a PO2 of 190 kPa (100% oxygen at 9 msw) during 60 minutes in an…
The primary objective in this study is to evaluate effectiveness of optimized high cervical epidural neurostimulation against placebo-stimulation in patients with intractable cervicogenic headache in a neurostimulation trial.
The aim of the present study is to compare the following transport characteristics for a modified 3.86% glucose PET preceded by a long (>8 hours) dwell with 3.86% glucose (PET A) and one preceded by a long dwell with 7.5% icodextrin (PET B),…
The objective of this study is to make a comparison between six different cornea topography measurement systems.
The aim of this study is to compare the PD20 values measured with the Vilbiss 646 jet nebulizer protocol and with the MedicAid nebulizing protocol in 20 subjects with respiratory symptoms suggestive of bronchial hyperreactivity.
The objective of this study is twofold.One aim of the study is to investigate the effects of tDCS (anodal, cathodal and sham) on balance correcting responses and simple reaction times in lower extremity muscles. We will determine whether the effects…
To investigate the accuracy of non-fasting lipid profiles versus fasting lipid profiles when lipid lowering therapy is aimed at recommended lipid treatment targets.
To validate and compare smartphone-connected blood pressure monitors produced by Withings, Qardio and iHealth with the gold standard and a validated automatic blood pressure monitor.
The main aim of this study is to collect normative data on the RANDI for several age groups.
The main objective is to demonstrate the activation of the efferent inhibitory cortico-olivocochlear pathway with otoacoustic emission of the ear contralateral to the side of stimulation with TMS. We expect the amplitude to decrease after TMS of the…
Primary objectives:1) Describe the PD effects on plasma ACTH and serum cortisol upon 100 µg hCRH injection with or without a preceding injection of 10 µg dDAVP 2 hours earlier and study the PK-PD relationship (*Block B*). In particular, the outcome…
1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol
The effect of a high-fat breakfast on intestinal permeability will be examined in lean and obese men to see if a fat load can induce increased intestinal permeability and it is a feasible challenge test to investigate effects of foods / ingredients…
The objective of the study is to investigate whether the Out-Of-Office BPM device of Microlife, the WatchBP O3, is comparable to the Spacelabs 90217 device at 24h BP measurement. Secondary objectives: To investigate whether the implemented features…
To determine which phMRI technique/approach will give the largest signal change after oral 5-HT challenge. We will compare task-related (modulation) phMRI to resting-state (challenge) phMRI and within the task-related phMRI four different paradigms…
To compare the burden for pregnant women and diagnostic capabilities of the oral glucose tolerance test (75g and 50g) and blood glucose samples during the day.
To prospectively compare NBI with HRE for the detection and differentiation of polyps in HPS in a large multicentre HPS cohort (n~125).
To obtain the reproducibility of the standing posture using with Der Wippe, a balancing device, with adjustable holder and acquire the 3D ultrasound of the spine of scoliotic patients
Primary objective:To show that addition of dead space to low-pressure nCPAP (which is usually not effective but can be relatively well tolerated) makes the therapy effective and diminishes the apnea hypopnea index with >10/hour in patients…