20 results
To investigate the acute responses occuring in the esophageal mucosa of EoE patients after local allergen provocation
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
This study aims to establish a plasmakinetic profile of GABA from tomatoes in healthy men and compare it to the kinetic profile of GABA from a supplement. In addition, the effects of glutamate (precursor of GABA) on the plasma-time curves of GABA…
Infant formulae with higher levels of milk fat result in improved microbiota composition as compared to standard formula.
3D-vision during robotic PJ and HJ biotissue anastomoses will reduce procedure time and improve surgical performance as compared to 2D-vision.
It is hypothesized that Ziverel tackles esophageal hypersensitivity by protecting the mucosal barrier function.
We expect that the shape of the cracker influences the amount of cheese consumers will add to their cracker (increase / decrease cheese intake). In addition, we expect that increased cheese viscosity increases oro-sensory exposure time (increased…
With personal control system, people feel more comfortable.
After calcitriol treatment, i. resting state striatal neuronal activity, i.e. BOLD signal, is increased and ii. visual food stimuli-induced neuronal activity of brain areas involved in food intake is reduced.
We hypothesize that trimetazidine improves left ventricular diastolic dysfunction in HFpEF, by improving mitochondrial function and increasing myocardial energy content
We hypothesize that TIPS placement has an significant effect on drug metabolism and bile acid metabolism.
In the current study, we will construct utility functions of two opioids, tapentadol and oxycodone, to assess the benefit/harm ratio of these drugs. To that end we will perform a PK PD study in healthy volunteers
There is a minimal interaction between edoxaban and tamoxifen and it can safely be used concomitantly
The purpose of this study is to investigate the effect of recorded music on surgical task performance and mental workload in a simulated setting. The study hypothesis is that preferred music will improve surgical task performance and decrease mental…
A relationship exists between a pharmacologic effect of ENX-201 and the plasma concentration
We hypothese that the health care for hand prosthesis users can be improved in terms of cost-effectiveness.
Acute whole-body heat treatment beneficially affects hepatic insulin sensitivity
We hypothesize that providing an attractive game with appropriate metaphors and personalized feedback and feedforward will positively impact the quality of home spirometry in asthmatic children.
Patients diagnosed with vasospastic angina (VSA) are at increased risk for cardiovascular events. VSA is characterized by endothelial dysfunction and abnormal vasodilatory reserve. Endothelin (ET)-1 is a potent vasoconstrictor peptide produced by…
1. Serum potassium in hemodialysis patients (CKD stage 5D) is mainly influenced by alterations in the internal potassium balance. 2. Higher dialysate potassium in CKD-5D increases the potassium erythrocyte concentration as proxy for TBK. 3. The…